72293-68-6

Basic information

• Product Name: (4-CHLORO-3-METHYL-PHENOXY)-ACETIC ACID HYDRAZIDE
• Synonyms: 2-(4-chloro-3-methylphenoxy)acetohydrazide(SALTDATA: FREE);2-(4-chloro-3-methyl-phenoxy)ethanehydrazide;Acetic acid, (4-chloro-3-methylphenoxy)-, hydrazide;BIM-0019400.P001;BRN 4683390;CBMicro_019307;Oprea1_253760;ST5182895
• CAS NO: 72293-68-6
• Molecular Formula: C₉H₁₁ClN₂O₂
• Molecular Weight: 214.65
• Mol File: 72293-68-6.mol
• Article Data: 5

Chemical Properties

• Boiling Point: 435.9°C at 760 mmHg
• Flash Point: 217.4°C
• Appearance: /
• Density: 1.279g/cm³
• Vapor Pressure: 8.43E-08mmHg at 25°C
• Refractive Index: 1.562
• CAS DataBase Reference: (4-CHLORO-3-METHYL-PHENOXY)-ACETIC ACID HYDRAZIDE(CAS DataBase Reference)
• NIST Chemistry Reference: (4-CHLORO-3-METHYL-PHENOXY)-ACETIC ACID HYDRAZIDE(72293-68-6)
• EPA Substance Registry System: (4-CHLORO-3-METHYL-PHENOXY)-ACETIC ACID HYDRAZIDE(72293-68-6)

Safety Data

• Hazardous Substances Data: 72293-68-6(Hazardous Substances Data)

Usage

General Description

(4-Chloro-3-methyl-phenoxy)-acetic acid hydrazide is a chemical compound that is often used in the synthesis of other organic compounds. It is a hydrazide derivative, meaning it contains a functional group with the formula -CONHNH2. This chemical is commonly used as a starting material in the production of pharmaceuticals and agrochemicals. It has the potential to react with other organic compounds to form new products with different chemical and biological properties. It may also be used as a reagent or intermediate in organic synthesis. The hydrazide group in this compound gives it potential for use in the creation of hydrazide-based derivatives with a variety of applications.

InChI:InChI=1/C9H11ClN2O2/c1-6-4-7(2-3-8(6)10)14-5-9(13)12-11/h2-4H,5,11H2,1H3,(H,12,13)

Upstream product

• 59-50-7 4-Chloro-3-methylphenol 
• 30406-61-2 ethyl 2-(4-chloro-3-methylphenoxy)acetate 
• 117554-55-9 Methyl 4-chloro-3-methylphenoxyacetate 

Downstream Products

• 72384-92-0 2-(3'-methyl-4'-chlorophenoxymethyl)-Δ²-1,3,4-oxadiazoline-5-thione 
• 84396-79-2 C₁₈H₂₀ClN₃O₂S 
• 84160-90-7 2-(4-Chloro-3-methyl-phenoxy)-N-(1,3-dioxo-1,3-dihydro-isoindol-2-yl)-acetamide 
• 78613-20-4 2-Amino-5-(4'-chloro-3'-methylphenoxymethyl)-1,3,4-oxadiazole 
• 125299-02-7 (4-Chloro-3-methyl-phenoxy)-acetic acid [2-oxo-1,2-dihydro-indol-(3Z)-ylidene]-hydrazide 
• 72293-70-0 2-[2-(4-Chloro-3-methyl-phenoxy)-acetyl]-5-methyl-2,4-dihydro-pyrazol-3-one 
• 76151-17-2 3-(4'-chloro-3'-methylphenoxymethyl)-4-p-tolyl-5-mercapto-1,2,4-triazole 
• 76152-00-6 3-(4'-chloro-3'-methylphenoxymethyl)-4-phenyl-5-mercapto-1,2,4-triazole 

Relevant articles and documents

Synthesis and biological evaluation of novel aryloxyacetic acid hydrazide derivatives as anticancer agents

In our continuing search for new anticancer agents, herein we report the synthesis of 2-(4-chloro-3-methylphenoxy)-N'-[(aryl)methylidene]acetohydrazides 3a–j and the evaluation of their anticancer activities on cell viability, morphological changes and ca

Synthesis, characterization and antimicrobial evaluation of novel imines and thiazolidinones

2-(4-Chloro-3-methylphenoxy)acetohydrazide (2) derived from ethyl 2-(4-chloro-3-methylphenoxy) acetate (1) was reacted with different aromatic aldehydes to yield N-(substituted benzylidiene)-2-(4-chloro-3- methylphenoxy)acetamide (3a-e). Cyclization of compound (3a-e) with thioglycolic acid yielded 2-(4-chloro- 3-methylphenoxy)-N-(4-oxo-2-arylthiazolidin-3-yl) acetamide (4a-e). The newly synthesized compounds were characterized on the basis of spectral studies and evaluated for antibacterial and antifungal activities.

Synthesis and Biological Activity of 3-Pentadecylaryloxyacetic Acids, Their Hydrazides and Cyclic Derivatives: Oxadiazoles and Pyrroles

Several 3-pentadecylaryloxyacetic acids (III), their hydrazides (IV), 2-amino-5-(3'-pentadecylaryloxymethyl)-1,3,4-oxadiazoles (V) and 1-(3'-pentadecylaryloxyacetamido)-2,5-dimethylpyrroles (VI) have been synthesised and evaluated for their biological activity.Some of the compounds exhibit strong antiinflammatory action in experimental animals.Presence of a long alkyl chain (C13H31) renders the compounds to be less toxic.