39502-80-2Relevant academic research and scientific papers
Hydride Transfers During Friedel-Crafts Reactions of 5,5-Dimethyl-4,5-dihydrofuran-2(3H)-one
Rae, Ian D.,Woolcock, Mark L.
, p. 1023 - 1029 (2007/10/02)
5,5-Dimethyl-4,5-dihydrofuran-2(3H)-one (4,4-dimethylbutyrolactone) reacts with toluene and with p-xylene in the presence of anhydrous aluminium chloride to give 4-methylpentanoyl benzenes with one, two or three methyls on the benzene ring.Reduction of the side chain has taken place by hydride transfer from an aromatic methyl, the resulting benzylic carbocation going on to form diarylmethanes by reaction with solvent molecules.
SYNTHESIS OF SUBSTITUTED 2,4,5-TRIMETHYLDIPHENYLMETHANES
Pozdnyakovich, Yu. V.,Borodovitsyn, V. V.,Pozdnyakovich, S. A.,Shein, S. M.
, p. 353 - 359 (2007/10/02)
2,5-Dimethyldiphenylmethane and its 2'- and 4'-methyl, chloro, and nitro derivatives were obtained by the reaction of substituted benzyl chlorides with p-xylene in the presence of ferric chloride and zinc stearate.The yields of the 2,5-dimethyldiphenylmethanes depend on the nature of the substituent in the benzyl chloride and decrease with the substituents in the order NO2>Cl>H>CH3.The 2' and 4'-methyl, chloro, and aminoderivatives of 2,4,5-trimethyldiphenylmethane were synthesized by chloromethylation of the obtained diphenylmethanes with paraform in acetic acid in the presence of zinc chloride followed by reduction of the 2,5-dimethyl-4-chloromethyldiphenylmethanes with zinc in acetic acid.
