39541-35-0

Upstream product

• 108-77-0 1,3,5-trichloro-2,4,6-triazine 
• 2627-86-3 (S)-1-phenyl-ethylamine 
• 536-57-2 p-toluene sulfinic acid 

Downstream Products

• 499213-07-9 2-chloro-4-N,N-dibenzylamino-6-N-((S)-α-methylbenzyl)amino-1,3,5-triazine 
• 142275-57-8 6-chloro-N-[(1S)-(1-phenylethyl)]-[1,3,5]triazine-2,4-diamine 
• 120436-14-8 (S)-2-chloro-4-(2-ethoxy-ethylamino)-6-(1-phenyl-ethylamino)-s-triazine 
• 499213-17-1 2-chloro-4,6-bis[N-(3-(N-(4-N,N-dibenzylamino-6-N-((S)-α-methylbenzyl)amino-1,3,5-triazin-2-yl)aminomethyl)phenylmethyl)amino]-1,3,5-triazine 
• 499213-12-6 2-N-(3-(aminomethyl)phenylmethyl)amino-4-N,N-dibenzylamino-6-N-((S)-α-methylbenzylamino)-1,3,5-triazine 

Relevant academic research and scientific papers

Efficient Synthesis of Sulfinate Esters and Sulfinamides via Activated Esters of p -Toluenesulfinic Acid

Sulfinate esters were prepared by the process of activating p -toluenesulfinic acid with either cyanuric chloride, methanesulfonyl chloride, or 1-ethyl-3-(3-dimethylaminopropyl)carbodiimide hydrochloride (EDC-HCl). Activation of p -toluenesulfinic acid with cyanuric chloride led to the formation of sulfinate esters that were accompanied by the formation of the corresponding sulfones. The use of methanesulfonyl chloride for activation via methanesulfonic p -toluenesulfinic anhydride afforded mixtures of sulfinate esters and methanesulfonates. The use of the carbodiimide EDC proved to yield the best results with the highly selective formation of the target sulfinate esters. The use of trimethylacetic p -toluenesulfinic anhydride or cyanuric chloride to achieve the synthesis of sulfinamides proved to be ineffective due to poor chemoselectivity of the nucleophilic attack on the activated p -toluenesulfinic acid anhydride. Ultimately, the use of EDC-HCl to form the sulfinamides proved to be the best pathway for synthesis.

Design and synthesis of a s-triazene based asymmetric organocatalyst and its application in enantioselective alkylation

A very efficient chiral organocatalyst was prepared from the readily available cyanuric chloride. The asymmetric catalyst exhibited a highly enantioselective catalytic performance for the alkylation of a glycinate Schiff base, which provides a useful procedure for the enantioselective synthesis of structurally diverse natural and unnatural α-alkyl-α-amino acids.

Aminotriazine 5-HT7 antagonists

The present studies have identified a series of aminotriazines as novel 5-HT7 receptor antagonists. Compounds 10 and 17 have high affinity for the 5-HT7 receptor and do not bind to either the 5-HT 2C or 5-HT6 re

A novel type of hydrogen-bonded assemblies based on the melamine·cyanuric acid motif

This paper reports the formation of novel hydrogen-bonded assemblies 13·CA obtained upon mixing cyanuric acid (CA) with melamine derivatives 1, in which two of the three possible H-bonding arrays have been blocked. The four components are held together by 9 hydrogen bonds and form a rigid planar structure in which a central CA (three ADA motifs: A = acceptor, D = donor) is hydrogen bonded to three peripheral melamine derivatives (DAD motif). Furthermore, the synthesis and assembly studies are described of hydrogen-bonded assemblies 2-4·CA, comprised of three melamine derivatives that are covalently connected, and CA. The overall thermodynamic stability of assemblies 2-4·CA is superior to 13·CA (ITm = 9 vs 3.6). The presence of the 2·CA complex in chloroform was confirmed by 1H NMR spectroscopy and MALDI-TOF mass spectrometry. Substitution of the trimelamines with chiral or fluorescent groups (R3) enabled the study of the assemblies by CD and fluorescence spectroscopy. Titration experiments revealed strongly enhanced stabilities even in the presence of polar solvents, such as THF and CH3OH. Depending on the polarity of the solvent, stacking between the planar assembly units was observed.

5-HT7 receptor antagonists

Amino-pyrimidine and amino-triazine derivatives having 5-HT7 antagonist activity for the treatment of sleeping disorders, depression, schizophrenia, anxiety, obsessive compulsive disorders, circadian rhythm disorders, ocular disorders and/or ce

Herbicidal substituted triazines

Herbicidal substituted triazines of the formula STR1 in which A1 represents optionally branched and optionally aryl-substituted alkanediyl, A2 represents optionally branched alkanediyl, Q represents oxygen, sulphur, NH or N-alkyl, R