39549-67-2

Upstream product

• 71182-78-0 N-Chlor-N'-p-brombenzoylacetamidin 
• 71565-90-7 N'-(4-bromo-benzoyl)-N,N-dimethyl-acetamidine 
• 90561-76-5 N-(4-bromo-benzyl)-acetamide 
• 698-67-9 p-bromobenzamide 
• 108-24-7 acetic anhydride 
• 3959-07-7 4-Bromobenzylamine 
• 177750-12-8 N-{1-(4-bromophenyl)vinyl}acetamide 
• 586-76-5 4-Bromobenzoic acid 
• 41882-25-1 4-Bromo-N-ethylbenzamide 

Downstream Products

• 1361032-67-8 5-(4-bromophenyl)-3-methyl-1-phenyl-1H-1,2,4-triazole 

Relevant academic research and scientific papers

Visible-Light-Driven Oxidation of N -Alkylamides to Imides Using Oxone/H 2 O and Catalytic KBr

Imides are prepared conveniently by visible-light-driven oxidations of various N -alkylamides under mild conditions. The majority of the reactions proceed efficiently by using Oxone as the oxidant in the presence of a catalytic amount of KBr in H 2 O/CH 2 Cl 2 under irradiation by an 8 W white LED at room temperature. Experimental studies suggest that an imine, obtained from the substrate amide via a radical process, is the key intermediate.

Transition-Metal- and Halogen-Free Oxidation of Benzylic sp 3 C-H Bonds to Carbonyl Groups Using Potassium Persulfate

Aryl carbonyl compounds including acetophenones, benzophenones, imides, and benzoic acids are prepared from benzyl substrates using potassium persulfate as oxidant with catalytic pyridine in acetonitrile under mild conditions. Neither transition metals nor halogens are involved in the reactions.

Oxidative Cleavage of Enamides with Hypervalent Iodine(III)/TMSN 3 under an Air Atmosphere

An oxidative cleavage of C-C double bonds of enamides promoted by hypervalent iodine(III)/TMSN 3 under an air atmosphere is developed. This reaction provides a new approach to construct various cyanobenzamides, which offers further synthetic potential for the preparation of industrial and pharmaceutical nitrogen- and oxygen-containing molecules, and exhibits good functional group tolerance, broad substrate scope and mild conditions.

Synthesis of 1,3,5-trisubstituted-1,2,4-triazoles by microwave-assisted N-acylation of amide derivatives and the consecutive reaction with hydrazine hydrochlorides

Facile and efficient procedures for the N-acylation reaction of amide derivatives with various acid anhydrides and the cyclization reaction of N-acylated amide derivatives with various hydrazine hydrochlorides were described. The reactions were carried out under microwave irradiation to give products in good yields in a few minutes. The synthesis of 1,3,5-trisubstituted- 1,2,4-triazoles from benzamides can also be accomplished in a simple one-pot sequential reaction.

Aerobic oxidation with N-hydroxyphthalimide catalysts in ionic liquid

N-Hydroxyphthalimide (NHPI)-catalyzed aerobic oxidations in the ionic liquids were examined for the first time. Both NHPI and its ionic derivative, 3-pyridinylmethyl-N-hydroxyphthalimide (Py-NHPI), were found to have better performance in the ionic liquid than in the conventional organic solvents for the aerobic oxidation of N-alkylamides to imides. On the other hand, Py-NHPI was found to be a much better catalyst than NHPI for the aerobic oxidation of benzylic compounds in the ionic liquid.