395664-56-9

Usage

Uses

Used in Pharmaceutical Industry:
2-Thiophenecarboxylic acid, 4-bromo-3-fluoro-, methyl ester is used as an intermediate in the synthesis of various pharmaceuticals. Its unique structure and functional groups make it a valuable building block for the development of new drugs with potential therapeutic applications.
Used in Agrochemical Industry:
In the agrochemical industry, 2-Thiophenecarboxylic acid, 4-bromo-3-fluoro-, methyl ester is utilized in the synthesis of various agrochemicals, such as pesticides and herbicides. Its chemical properties allow for the creation of effective compounds that can protect crops from pests and diseases.
Used in Chemical Research and Development:
2-Thiophenecarboxylic acid, 4-bromo-3-fluoro-, methyl ester is employed as a research compound in the field of chemical research and development. Its unique structure and properties make it an interesting subject for studying various chemical reactions and exploring its potential applications in different areas.
Used in Production of Fine Chemicals:
2-Thiophenecarboxylic acid, 4-bromo-3-fluoro-, methyl ester is also used in the production of fine chemicals, which are high-purity chemicals used in various industries, such as pharmaceuticals, cosmetics, and fragrances. The synthesis of fine chemicals often requires specific intermediates, and 2-Thiophenecarboxylic acid, 4-bromo-3-fluoro-, methyl ester serves as a key component in this process.
It is important to handle 2-Thiophenecarboxylic acid, 4-bromo-3-fluoro-, methyl ester with care, as it may have potential health and environmental hazards. Proper safety measures should be taken during its synthesis, storage, and use to minimize any risks associated with this chemical compound.

InChI:InChI=1/C6H4BrFO2S/c1-10-6(9)5-4(8)3(7)2-11-5/h2H,1H3

Upstream product

• 395664-58-1 4,5-dibromo-3-fluoro-thiophene-2-carboxylic acid methyl ester 
• 32431-84-8 3-fluoro-2-thiophenecarboxylic acid 
• 100421-52-1 methyl 3-fluorothiophene-2-carboxylate 
• 22288-78-4 Methyl 3-aminothiophene-2-carboxylate 

Downstream Products

• 395664-68-3 4-(4-dodecyloxy-phenyl)-3-fluoro-thiophene-2-carboxylic acid methyl ester 

Relevant academic research and scientific papers

NOVEL HETEROCYCLIC COMPOUNDS AS BET INHIBITORS

Provided are heterocyclic compounds of formula (I) as bromodomain and extraterminal (BET) inhibitors, pharmaceutical compositions comprising the compounds, their synthesis and their use for treating diseases and conditions wherein inhibition of one or more BET bromodomains provides a benefit.

Five-membered heterocyclic oxo carboxylic acid compound and medical application thereof

The invention relates to a five-membered heterocyclic oxo carboxylic acid compound and a medical application thereof. Specifically, the invention relates to a compound, a pharmaceutical salt, a prodrug, a hydrate, a solvate or a crystal form as shown in a formula (I), and also relates to a preparation method of the compound, a pharmaceutical composition containing the compound and an application of the pharmaceutical composition as a secretion regulator of interferon type I, especially as an STING agonist in preparation of medicines for preventing and/or treating I-type interferon related diseases.

FACTOR XIa INHIBITORS

The present invention provides a compound of Formula (I); and pharmaceutical compositions comprising one or more said compounds, and methods for using said compounds for treating or preventing thromboses, embolisms, hypercoagulability or fibrotic changes. The compounds are selective Factor XIa inhibitors or dual inhibitors of Factor XIa and plasma kallikrein.

Ring fluorinated thiophenes: Applications to liquid crystal synthesis

Ring fluorinated thiophenes were synthesized via a Balz-Schiemann fluorination approach and were successfully employed in the synthesis of liquid crystals using regioselective electrophilic bromination and regioselective Suzuki coupling chemistry.