395682-83-4

Upstream product

• 20697-04-5 3-chlorostyrene oxide 
• 74-89-5 methylamine 
• 41011-01-2 2-bromo-1-(3-chloro-phenyl)-ethanone 
• 117538-45-1 2-bromo-1-(3-chlorophenyl)ethanol 

Downstream Products

• 1375709-01-5 8-Chloro-2-(3-chlorophenyl)-4-methyl-2,3,4,5-tetrahydropyrido[3,2-f][1,4]oxazepine 
• 1375708-98-7 1-(3-chlorophenyl)-2-(((2,6-dichloropyridin-3-yl)methyl)(methyl)amino)ethanol 
• 1375706-42-5 2-(3-Chlorophenyl)-4-methyl-N-(5-(3-methyl-1H-1,2,4-triazol-1-yl)pyridin-2-yl)-2,3,4,5-tetrahydropyrido[3,2-f][1,4]oxazepin-8-amine 

Relevant academic research and scientific papers

Compounds and Their Use for Treatment of Amyloid Beta-Related Diseases

The present invention relates to novel compounds of formula (I) and pharmaceutically acceptable salts thereof, pharmaceutical compositions comprising said compounds, processes for making said compounds, and their use as medicaments for treatment and/or prevention of Aβ-related diseases.

2-Aryl-2-hydroxyethylamine substituted 4-oxo-4,7-dihydrothieno[2,3-b]pyridines as broad-spectrum inhibitors of human herpesvirus polymerases

A novel series of 2-aryl-2-hydroxyethylamine substituted 4-oxo-4,7-dihydrothieno[2,3-b]pyridine-5-carboxamides have been identified as potent antivirals against human herpesviruses. These compounds demonstrate broad-spectrum inhibition of the herpesvirus polymerases HCMV, HSV-1, EBV, and VZV with high specificity compared to human DNA polymerases.