3957-71-9

Usage

Uses

Used in Organic Synthesis:
2,6-DI-TERT-BUTYL-4-THIOCYANATO-PHENOL is used as a reagent in organic synthesis for its ability to participate in various chemical reactions, facilitating the creation of a range of organic compounds.
Used in Chemical Research:
In the field of chemical research, 2,6-DI-TERT-BUTYL-4-THIOCYANATO-PHENOL serves as a valuable tool for studying the properties and reactions of thiocyanate derivatives and phenolic compounds.
Used as an Intermediate in Compound Production:
2,6-DI-TERT-BUTYL-4-THIOCYANATO-PHENOL is utilized as an intermediate in the production of various compounds, contributing to the synthesis of pharmaceuticals, agrochemicals, and other specialty chemicals.
Used in Pharmaceutical Research:
2,6-DI-TERT-BUTYL-4-THIOCYANATO-PHENOL is of interest in pharmaceutical research due to its potential pharmacological and biological activities, which may lead to the development of new therapeutic agents.
Used in Safety and Handling Protocols:
Given its potential hazards as a chemical substance, 2,6-DI-TERT-BUTYL-4-THIOCYANATO-PHENOL is also used in the development of safety and handling protocols to ensure the protection of researchers and the environment during its application in various industries.

Upstream product

• 128-39-2 2,6-di-tert-butylphenol 
• 333-20-0 potassium thioacyanate 
• 2290-65-5 trimethylsilyl isothiocyanate 
• 540-72-7 sodium thiocyanide 

Downstream Products

• 6386-58-9 4,4'-dithiobis(2,6-di-tert-butylphenol) 
• 950-59-4 4-hydroxy-3,5-di-tert-butylthiophenol 
• 105648-42-8 C₁₇H₂₇NO₂S*ClH 
• 114811-87-9 C₃₃H₄₈N₄O₂S 
• 2444-28-2 2,6-di-tert-butyl-4-hydroxyphenol 
• 719-22-2 2,6-Di-tert-butyl-1,4-benzoquinone 
• 81056-41-9 7-tert-Butyl-2-methyl-5-thiocyanatobenzoxazol 
• 105648-50-8 2,4,6-tris(4-hydroxy-3,5-di-tert-butylphenylthio)-symm-triazine 
• 162933-23-5 6-<3,5-di(tert-butyl)-4-hydroxyphenylthio>-2,4-bis(trichloromethyl)-sym-triazene 
• 4673-51-2 4,4'-thiobis[2,6-bis(tert-butyl)phenol] 
• 26532-80-9 2,6-di-tert-butyl-4-(methylsulfanyl)phenol 
• 26532-81-0 4-tert.-Butylmercapto-2,6-di-tert.-butyl-phenol 
• 94092-37-2 2,6-bis(1,1-dimethylethyl)-4-(methylsulfinyl)phenol 
• 55485-65-9 <1-Hydroxy-2,6-di-tert.-butyl-phenyl-(4)>-essigsaeurethiolester 

Relevant academic research and scientific papers

Synthesis method of dithiobis-butyl phenol and analogue thereof

The invention provides a synthesis method of dithiobis-butyl phenol and an analogue thereof. The synthesis method provided by the invention has the advantages of few steps, high yield and high purity of the obtained product. The dithiobis-butyl phenol and the analogue thereof synthesized by the invention can be used for preparing medicines for preventing and/or treating coronavirus pneumonia (containing COVID-19).

Thiocyanation of aromatic and heteroaromatic compounds with 1-Chloro-1,2-benziodoxol-3-(1H)-one and (Trimethylsilyl)isothiocyanate

Thiocyanation of aromatic compounds has been investigated using the combination of 1-chloro-1,2-benziodoxol-3-(1H)-one (1) and (trimethylsilyl)isothiocyanate (TMSNCS). The reaction with electron rich aromatic compounds proceeded smoothly to provide the th

Probucol derivative, preparation method and application thereof

The invention relates to the fields of compounds, and specifically relates to a probucol derivative, a preparation method and the application thereof. The probucol derivative has a structure shown asa general formula I. The probucol derivative provided by the invention can be used for prevention and curing of vascular diseases such as diabetes and cardiovascular and cerebrovascular diseases or complications thereof, can be used for reducing blood glucose, reducing blood fat, reducing cholesterol, reducing the weight, reducing triglyceride, resisting inflammation and oxidation and the like effectively, and has a wide application prospect.

Phenolic thioetheramides

The present invention relates to phenolic thioetheramides of the formula STR1 wherein R1 and R2 are tert-alkyl or phenyl, Alk1 and Alk2 are alkylene; X is sulfur or oxygen, m is 0, 1, or 2; and R is STR2 wherein R3 and R4 are hydrogen or alkyl and Alk3 is alkylene.

2-AMINOETHANESULFONIC ACID DERIVATIVES OF 3,5-DISUBSTITUTED-4-HYDROXY-PHENOLIC THIOETHERS

The present invention relates to compounds of the Formula I:wherein R1 and R2 are the same or different and independently represent tert-alkyl, halogen, or phenyl; Alk 1 represents straight or branched chain alkylene of 2 to 10 carbon atoms which can optionally be substituted by hydroxy, provided that said hydroxy is not attached to a carbon which is adjacent to sulfur or oxygen, X represents sulfur or oxygen, and Alk 2 represents straight or branched chain alkylene of 1 to 4 carbon atoms; and the pharmaceutically acceptable salts thereof. These compounds are specific 5-lipoxygenase inhibitors and are useful as anti-inflammatory and anti-allergy agents and in the treatment of conditions mediated by 5-lipoxygenase

Method of stimulating superoxide generation

The present invention is directed to a method of stimulating superoxide generation using phenolic thioethers which stimulate the generation of superoxide.

3,5-DITERTIARYBUTYL-4-HYDROXYPHENYL, 1,3,4-THIADIAZOLES AND OXADIAZOLES LINKED BY CARBON, OXYGEN, AND SULFUR RESIDUES

The novel 3,5-ditertiarybutyl-4-hydroxyphenylthio-1,3,4-thiadiazoles and oxadiazoles and 3,5-ditertiarybutyl-4-hydroxyphenylmethanone-l,3,4-thiadiazoles and oxadiazoles and related compounds of the present invention are antiinflammatory agents having activity as inhibitors of 5-lipoxygenase, cyclooxygenase or both

Acylaminoalkylpyridineamides as inhibitors of metastasis

The present invention relates to a method of inhibiting tumor metastasis in an aminal by administering to an animal in need of such treatment an acrylaminoalkylpryridineamides represented by the formula STR1 wherein: R1 and R2 are the same or different members of the group consisting of halo, phenyl, substituted phenyl and a STR2 group wherein n, m and p are independently an integer of from 1 to 8 provided n+m+p is equal to or less than 10; x is thio or sulfinyl; Alk1 is straight or branched chain lower alkylene of 1 to 6 carbon atoms, R3 is hydrogen or lower alkyl, Alk2 is straight or branched chain alkylene of 1 to 4 carbon atoms; R4 is selected from the group consisting of hydrogen, halo, hydroxy, lower alkyl and lower alkoxy; or a pharmaceutically acceptable salt thereof, in an amount effective to inhibit tumor metastasis.

5-LIPOXYGENASE INHIBITORS

This invention encompasses compounds and methods for inhibiting lipoxygenase and includes a pharmaceutical composition comprising a pharmaceutical carrier and an effective lipoxygenase inhibiting amount of a compound of the formula: wherein R1 and R2 are the same or different members of the group consisting of tert-alkyl of 4 to 10 carbon atoms; and R3 is wherein R4 is hydrogen or lower alkyl; wherein R6 and R7 may be the same or different and are alkyl of 1 to 4 carbon atoms; or and the pharmaceutically acceptable salts thereof. The compounds and pharmaceutical formulations of the present invention are 5-lipoxygenase inhibitors and, therefore, are useful in the treatment of local and systemic inflammation, allergy and hypersensitivity reactions and other disorders in which agents formed in the 5-lipoxygenase metabolic pathway are involved.