39573-69-8

Basic information

• Product Name: Pyrrolo[1,2-a]pyrazine, 1-phenyl-
• CAS NO: 39573-69-8
• Molecular Formula: C13H10N2
• Molecular Weight: 194.236
• Mol File: 39573-69-8.mol

Chemical Properties

• CAS DataBase Reference: Pyrrolo[1,2-a]pyrazine, 1-phenyl-(CAS DataBase Reference)
• NIST Chemistry Reference: Pyrrolo[1,2-a]pyrazine, 1-phenyl-(39573-69-8)
• EPA Substance Registry System: Pyrrolo[1,2-a]pyrazine, 1-phenyl-(39573-69-8)

Safety Data

• Hazardous Substances Data: 39573-69-8(Hazardous Substances Data)

Upstream product

• 2689-59-0 (furan-2-yl)(phenyl)methanone 
• 136927-64-5 1-chloropyrrolo[1,2-a]pyrazine 
• 98-80-6 phenylboronic acid 
• 98-88-4 benzoyl chloride 
• 111609-55-3 1-phenyl-3,4-dihydropyrrolo<1,2-a>pyrazine 

Downstream Products

• 1613164-79-6 6-bromo-1-phenylpyrrolo[1,2-a]pyrazine 
• 1613164-93-4 6-methyl-1-phenylpyrrolo[1,2-a]pyrazine 
• 1613164-94-5 1,6-diphenylpyrrolo[1,2-a]pyrazine 
• 1613165-15-3 (R)-2-benzyl-1-phenyl-1,2,3,4-tetrahydropyrrolo[1,2-a]pyrazine 
• 1613165-32-4 C₁₈H₂₂N₂O₂ 
• 1613165-33-5 tert-butyl benzyl(2-(2-benzyl-1H-pyrrol-1-yl)ethyl)carbamate 
• 1613165-13-1 C₂₁H₁₉N₂⁽¹⁺⁾*Br^(1-) 
• 1613165-14-2 C₂₆H₂₁N₂⁽¹⁺⁾*Br^(1-) 
• 1613164-95-6 2-benzyl-1-phenylpyrrolo[1,2-a]pyrazin-2-ium bromide 
• 1134309-00-4 6-acetyl-1-phenylpyrrolo[1,2-a]pyrazine 
• 1133789-00-0 6-formyl-1-phenylpyrrolo[1,2-a]pyrazine 
• 911717-09-4 1-phenyl-6-(trifluoroacetyl)pyrrolo[1,2-a]pyrazine 

Relevant articles and documents

EIS INHIBITORS

Compounds and compositions are disclosed, which are useful as inhibitors of acetyltransferase Eis, a mediator of kanamycin resistance in Mycobacterium tuberculosis.

Combating Enhanced Intracellular Survival (Eis)-Mediated Kanamycin Resistance of Mycobacterium tuberculosis by Novel Pyrrolo[1,5-a]pyrazine-Based Eis Inhibitors

Tuberculosis (TB) remains one of the leading causes of mortality worldwide. Hence, the identification of highly effective antitubercular drugs with novel modes of action is crucial. In this paper, we report the discovery and development of pyrrolo[1,5-a]p

Iridium-catalyzed asymmetric hydrogenation of pyrrolo[1,2- a ]pyrazinium salts

Highly enantioselective iridium-catalyzed hydrogenation of pyrrolo[1,2-a]pyrazinium salts has been achieved, providing a direct access to chiral 1,2,3,4-tetrahydropyrrolo[1,2-a]pyrazine derivatives with up to 95% ee. The key feature of the reaction is the addition of cesium carbonate, which increases the conversion and prohibits the racemization pathway of products.

RECYCLIZATION OF PYRROLOPYRAZINIUM SALTS INTO 6- AND 8-AMINOINDOLIZINES

Recyclization of 3-alkylpyrrolopyrazinium salts in the presence of base afforded derivatives of 6-aminoindolizine.Rearrangement of 1,3-dialkylpyrrolopyrazinium salts proceeded in two directions, giving rise to both 6- and 8-aminoindolizines,