39600-44-7

Basic information

• Product Name: N-(methoxcarbonylmethyl)aminomethylphosphonic acid (Glyphosate methyl ester)
• Synonyms: N-(methoxcarbonylmethyl)aminomethylphosphonic acid (Glyphosate methyl ester);N-(methoxcarbonylmethyl)aminomethylphosphonic acid;(2-Methoxy-2-oxo-ethyl)aminomethylphosphonic acid
• CAS NO: 39600-44-7
• Molecular Formula: C₄H₁₀NO₅P
• Molecular Weight: 366.199322
• Mol File: 39600-44-7.mol
• Article Data: 5

Chemical Properties

• Appearance: /
• CAS DataBase Reference: N-(methoxcarbonylmethyl)aminomethylphosphonic acid (Glyphosate methyl ester)(CAS DataBase Reference)
• NIST Chemistry Reference: N-(methoxcarbonylmethyl)aminomethylphosphonic acid (Glyphosate methyl ester)(39600-44-7)
• EPA Substance Registry System: N-(methoxcarbonylmethyl)aminomethylphosphonic acid (Glyphosate methyl ester)(39600-44-7)

Safety Data

• Hazardous Substances Data: 39600-44-7(Hazardous Substances Data)

Usage

General Description

Glyphosate methyl ester, also known as N-(methoxycarbonylmethyl)aminomethylphosphonic acid, is a derivative of the commonly used herbicide glyphosate. It is a phosphonic acid compound that is used in agricultural applications to control the growth of unwanted plants and weeds. Glyphosate methyl ester works by inhibiting the enzyme 5-enolpyruvylshikimate-3-phosphate synthase (EPSPS), which is essential for the synthesis of aromatic amino acids in plants. This disruption leads to the death of the targeted plants. Glyphosate methyl ester is typically applied as an herbicidal spray and is known for its ability to effectively control a wide range of plant species. However, the use of glyphosate methyl ester has been subject to controversy due to concerns about its potential environmental and health impacts.

Upstream product

• 67-56-1 methanol 
• 1071-83-6 N-(phosphonemethyl)glycine 

Downstream Products

• 59115-06-9 N-phosphonomethylglycine 2-methyl-2-phenyl hydrazide 
• 39600-54-9 glyphosate amide 
• 1071-83-6 N-(phosphonemethyl)glycine 

Relevant articles and documents

Heterocycle-containing glyphosate derivative, and preparation method and application thereof

The invention provides a heterocycle-containing glyphosate derivative. The heterocycle-containing glyphosate derivative has a structure which is shown as the formula (I); in the formula, M1 is selected from H, NH4, K or Na; M2 is selected from H, NH4, K or Na; n is 0 to 5; R is selected from the substances which are shown as the formula in the specification, wherein R' is selected from an alkyl of H or C1 to C4. The heterocycle-containing glyphosate derivative provided by the invention is used as an herbicide, is prevented from being compounded with other pesticides to produce chemical reactions, and is simple in using method and good in pesticide effect. A synthesis method provided by the invention is simple, green and environmentally-friendly, and has good atom economy.

Chemical and Mutagenic Analysis of Aminomethylphosphonate Biodegradation

Utilization of aminomethyl-, N-methylaminomethyl-, N,N-dimethylaminomethyl-, and N-acetylaminomethylphosphonate by Escherichia coli as a sole source of phosphorus during growth resulted in the extracellular generation of N-methylacetamide, N,N-dimethylacetamide, trimethylamine, and N-methylacetamide, respectively.Product identification relied on synthesis of (13)C-enriched aminomethylphosphonates followed by (1)H NMR analysis of products isolated from the biodegradation of the labeled and unlabeled phosphorus sources.To circumvent the requirement of an intact cell for carbon to phosphorus bond degradation, transposon mutagenesis was exploited as a complement to the chemical analysis.E. coli K-12 were infected with λTn5.Colonies resistant to kanamycin were selected and then screened for loss of the ability to use ethylphosphonate as a sole source of phosphorus.The mutant identified, E. coli SL724, was also unable to degrade aminomethylphosphonates.This combination of chemical and mutagenic analysis points toward a shared mechanism between alkyl- and aminomethylphosphonate biodegradation.

Herbicidal compositions and methods employing esters of N-phosphonomethylglycine

N-phosphonomethylglycine and novel derivatives thereof useful as phytotoxicants or herbicides.