39602-14-7Relevant academic research and scientific papers
Syntheses of acridines and quinazoline-2,4(1H,3H)-dithiones by rearrangements of N-Heterocyclic carbenes of indazole
Guan, Zong,Gjikaj, Mimoza,Schmidt, Andreas
, p. 2356 - 2367 (2014/12/11)
N-Heterocyclic carbenes of indazole which are arylated at N1 (1-aryl-indazol-3-ylidenes) have been generated by deprotonation of the corresponding indazolium salts. On deprotonation with potassium carbonate, potassium phosphate or tert-butanolate in dioxane or toluene at reflux temperature, a rearrangement to acridines took place. Deprotonation with n-butyllithium in THF at room temperature in the presence of carbon disulfide gave quinazoline-2,4(1H,3H)-dithiones by a new rearrangement reaction.
