396090-35-0

Upstream product

• 871503-96-7 3,5-dimethoxy-2H-pyridine-1-carboxylic acid allyl ester 
• 396090-17-8 prop-2-enyl 5-hydroxy-3-oxo-1,2,6-trihydropyridine-1-carboxylate 
• 2457-47-8 3,5-dichloropyridine 
• 18677-48-0 3,5-dimethoxypyridine 
• 15100-75-1 L-phenylalanine tert-butyl ester hydrochloride 
• 396090-18-9 prop-2-enyl 3-oxo-5-[(2,4,6-trimethylphenyl)sulfonyloxy]-1,2,6-trihydropyridine-1-carboxylate 

Downstream Products

• 396090-39-4 Ach-Phe t-butyl ester 

Relevant academic research and scientific papers

"@-Tides": The 1,2-dihydro-3(6h)-pyridinone unit as a β-strand mimic

The cyclic amino acid surrogate 1 was designed to mimic the extended conformation of a peptide unit and to provide hydrogen bond donor and acceptor functions conducive to β-sheet formation. A convenient synthesis of this unit and solution and solid-phase methods for its incorporation into an oligomer alternating with peptide units have been devised. The resulting "@-tides", as these oligomers have been designated, show a high propensity for self-association in comparison to oligopeptides; insights into the structure and dynamical properties of their antiparallel dimers have been obtained by NMR.