396102-32-2Relevant academic research and scientific papers
Total synthesis of (±)-herbertenediol
Srikrishna,Satyanarayana
, p. 2892 - 2900 (2007/10/03)
A formal total synthesis of the sesquiterpene (±)-herbertenediol and its dimers mastigophorenes A-D has been accomplished, starting from vanillin via 2,3-dimethoxy-5-methylbenzaldehyde. A combination of Claisen rearrangement and ring-closing metathesis reactions were employed for the generation of the two vicinal quaternary carbons on a cyclopentane ring.
New route to herbertanes via a Suzuki cross-coupling reaction: Synthesis of herbertenediol
Abad, Antonio,Agulló, Consuelo,Cu?at, Ana C,Jiménez, Diego,Perni, Remedios H
, p. 9727 - 9735 (2007/10/03)
The synthesis of herbertenediol, a relevant member of the herbertane-type sesquiterpene family, is described. The synthesis is based on a new general approach to this group of sesquiterpenes where the herbertane skeleton is constructed using a Suzuki cross-coupling reaction and a [2,3]-sigmatropic Still-Wittig rearrangement as key synthetic steps.
New total synthesis of (±)-herbertene, (±)-β-herbertenol and (±)-herbertenediol
Gupta,Pal,Roy,Mukherjee
, p. 7563 - 7566 (2007/10/03)
The total syntheses of the herbertane sesquiterpenes (±)-herbertene (1), (±)-β-herbertenol (2) and (±)-herbertenediol (5) have been successfully accomplished involving copper-catalysed conjugate addition of Grignard reagents to unsaturated compounds and α
