39624-13-0Relevant academic research and scientific papers
A minimalistic approach to develop new anti-apicomplexa polyamines analogs
Panozzo-Zénere, Esteban A.,Porta, Exequiel O.J.,Arrizabalaga, Gustavo,Fargnoli, Lucía,Khan, Shabana I.,Tekwani, Babu L.,Labadie, Guillermo R.
, p. 866 - 880 (2017/12/13)
The development of new chemical entities against the major diseases caused by parasites is highly desired. A library of thirty diamines analogs following a minimalist approach and supported by chemoinformatics tools have been prepared and evaluated agains
Hybrid Organic–Inorganic Rotaxanes, Including a Hetero-Hybrid [3]Rotaxane Featuring Two Distinct Heterometallic Rings and a Molecular Shuttle
Timco, Grigore A.,Fernandez, Antonio,Kostopoulos, Andreas K.,Charlton, Jodie F.,Lockyer, Selena J.,Hailes, Thomas R.,Adams, Ralph W.,McInnes, Eric J. L.,Tuna, Floriana,Vitorica-Yrezabal, Inigo J.,Whitehead, George F. S.,Winpenny, Richard E. P.
supporting information, p. 10919 - 10922 (2018/08/01)
[2] and [3] hybrid rotaxanes are reported based on {Ti7M} rings (M is a trivalent metal such as FeIII or GaIII). NMR studies show that [2]rotaxanes can act as molecular shuttles, while EPR studies of [3]rotaxanes show weak interactions between the paramagnetic components of the supramolecular assemblies.
Synthesis and antikinetoplastid activity of a series of N,N×-substituted diamines
Caminos, Andrea P.,Panozzo-Zenere, Esteban A.,Wilkinson, Shane R.,Tekwani, Babu L.,Labadie, Guillermo R.
supporting information; experimental part, p. 1712 - 1715 (2012/04/10)
A series of 25 N,N×-substituted diamines were prepared by controlled reductive amination of free aliphatic diamines with different substituted benzaldehydes. The library was screened in vitro for antiparasitic activity on the causative agents of human Afr
Method of potentiating cell-mediated immunity utilizing polyamine derivatives
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, (2008/06/13)
This invention relates to a method of potentiating cell-mediated immunity which comprises administering to a patient a cell-mediated immunity potentiating amount of a compound of the formula: or a pharmaceutically acceptable salt thereof, wherein m is
