39662-50-5

Basic information

• Product Name: 1-[2-(3,4-dimethoxyphenyl)ethyl]-5-hydroxy-2-pyrrolidinone
• Synonyms: 1-[2-(3,4-dimethoxyphenyl)ethyl]-5-hydroxy-2-pyrrolidinone
• CAS NO: 39662-50-5
• Molecular Weight: 265.309
• Mol File: 39662-50-5.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: 1-[2-(3,4-dimethoxyphenyl)ethyl]-5-hydroxy-2-pyrrolidinone(CAS DataBase Reference)
• NIST Chemistry Reference: 1-[2-(3,4-dimethoxyphenyl)ethyl]-5-hydroxy-2-pyrrolidinone(39662-50-5)
• EPA Substance Registry System: 1-[2-(3,4-dimethoxyphenyl)ethyl]-5-hydroxy-2-pyrrolidinone(39662-50-5)

Safety Data

• Hazardous Substances Data: 39662-50-5(Hazardous Substances Data)

Upstream product

• 40173-90-8 3,4-dimethoxyphenethyl bromide 
• 39662-45-8 N-<2-(3,4-dimethoxyphenyl)ethyl>succinimide 
• 120-20-7 2-(3,4-dimethoxyphenyl)-ethylamine 

Downstream Products

• 15889-93-7 (+/-)-crispine A 

Relevant articles and documents

Zinc-catalyzed selective reduction of cyclic imides with hydrosilanes: Synthesis of ω-hydroxylactams

Cyclic imides were selectively reduced to the corresponding ω-hydroxylactams in high yields with (EtO)3SiH (triethoxysilane) or PMHS (polymethylhydrosiloxane) under catalysis of zinc diacetate dehydrate [Zn(OAc)2 2H2O] (10%) and tetramethylethylenediamine (TMEDA) (10%). This catalytic protocol showed good functional group tolerance as well as excellent regioselectivity for unsymmetrical imides bearing coordinating groups adjacent to the carbonyl.