39685-31-9

Basic information

• Product Name: cefuracetime
• Synonyms: cefuracetime;(7R)-7-[2-(2-Furyl)-2-[(Z)-methoxyimino]acetylamino]cepham-3-ene-4-carboxylic acid;640/1;660-1;7R)-3-(acetoxymethyl)-7-((Z)-2-(furan-2-yl)-2-(methoxyimino)acetamido)-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid;Cefuroxime Sodium EP Impurity B;Cefuroxime Sodium Impurity B (EP);Cefuroxime Sodium Impurity G (EP)
• CAS NO: 39685-31-9
• Molecular Formula: C₁₇H₁₇N₃O₈S
• Molecular Weight: 423.4
• EINECS: 254-592-2
• Mol File: 39685-31-9.mol
• Article Data: 3

Chemical Properties

• Boiling Point: °Cat760mmHg
• Flash Point: °C
• Appearance: /
• Density: 1.63g/cm³
• Refractive Index: 1.69
• Storage Temp.: -20°C Freezer, Under inert atmosphere
• Solubility: DMSO (Slightly), Methanol (Slightly, Sonicated)
• PKA: 2.66±0.50(Predicted)
• CAS DataBase Reference: cefuracetime(CAS DataBase Reference)
• NIST Chemistry Reference: cefuracetime(39685-31-9)
• EPA Substance Registry System: cefuracetime(39685-31-9)

Safety Data

• Hazardous Substances Data: 39685-31-9(Hazardous Substances Data)

Usage

Uses

Cefuracetime is an impurity of Cefuroxime, which is an antibacterial.

InChI:InChI=1/C17H17N3O8S/c1-8(21)28-6-9-7-29-16-12(15(23)20(16)13(9)17(24)25)18-14(22)11(19-26-2)10-4-3-5-27-10/h3-5,12,16H,6-7H2,1-2H3,(H,18,22)(H,24,25)/b19-11-/t12-,16-/m1/s1

Upstream product

• 17090-71-0 furan-2-yl-oxo-acetaldehyde 
• 67-62-9 O-Methylhydroxylamin 
• 957-68-6 7-Aminocephalosporanic acid 
• 97148-39-5 (Z)-2-methoxyimino-2-(furyl-2-yl)acetic acid ammonium salt 

Downstream Products

• 56271-94-4 (6R,7R)-7-[2-(2-furyl)-2-(methoxyimino)acetamido]-3-hydroxymethyl-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid 
• 55268-75-2 Cefuroxime 

Relevant articles and documents

Method for synthesizing 3-decarbamoyl-acetyl-cefuroxime acid compound

The invention provides a method for synthesizing a 3-decarbamoyl-acetyl-cefuroxime acid compound. The method comprises the following steps: taking 2-(2-furyl)-2-oxo-acetaldehyde, 7-aminocephalosporanic acid and methoxyamine as raw materials; reacting the raw materials in a reaction solvent under the combined action of a first catalyst, an oxidizing agent and a second catalyst; and carrying out chromatography to obtain the 3-deaminobenzoyl acetyl cefuroxime acid compound. By using the method, the process steps are simple, the byproduct is mainly water, a large amount of other wastes do not exist, and the subsequent treatment cost and the environmental protection pressure are low.

A adopt the particle process crystal product molecular assembly and shape optimization technique of the new crystalline form of cefuroxime sodium compound and preparation (by machine translation)

The invention discloses a new crystalline form of cefuroxime sodium compound and its crystallization preparation method, the new crystalline form of the compound is sodium [...] particle process crystal product molecular assembly and shape optimization technique to prepare. The stability tests prove that the new crystalline form of compound has high purity, low impurity content, guide the low moisture, the good characteristic of stability. At the same time, the invention also discloses the preparation of cefuroxime sodium employing the above described head-injection for the preparation. (by machine translation)