397-10-4Relevant articles and documents
Umpolung amination: Nickel-catalyzed coupling reactions of N,N-dialkyl-N-chloroamines with diorganozinc reagents
Barker, Timothy J.,Jarvo, Elizabeth R.
supporting information; experimental part, p. 15598 - 15599 (2010/01/29)
(Chemical Equation Presented) N,N-Dialkyl-N-chloroamines are an effective source of electrophilic nitrogen for nickel-catalyzed coupling with diarylzinc reagents. A variety of N-chloroamines as well as organozinc reagents react smoothly under the reaction conditions. A one-pot procedure that circumvents the need to isolate the N-chloroamines is described.