39703-08-7Relevant academic research and scientific papers
Avarol derivatives as competitive AChE inhibitors, non hepatotoxic and neuroprotective agents for Alzheimer's disease
Tommonaro, Giuseppina,García-Font, Nuria,Vitale, Rosa Maria,Pejin, Boris,Iodice, Carmine,Ca?adas, Sixta,Marco-Contelles, José,Oset-Gasque, María Jesús
, p. 326 - 338 (2016/07/07)
Avarol is a marine sesquiterpenoid hydroquinone, previously isolated from the marine sponge Dysidea avara Schmidt (Dictyoceratida), with antiinflammatory, antitumor, antioxidant, antiplatelet, anti-HIV, and antipsoriatic effects. Recent findings indicate
Total synthesis of polyprenylhydroquinols and benzoquinones
Bouzbouz, Samir,Kirschleger, Bernard,Villieras, Jean
, p. 67 - 84 (2007/10/03)
The total synthesis of polyprenylhydroquinols and benzoquinones is described.First, two appropriate aromatic allyl carbonates (moieties with one and two prenyls) and two activated bifunctional terpenyl derivatives (moieties with two and three prenyls) were synthesized.These molecules were then reacted together using a highly regio- and stereoselective coupling with Pd(PPh3)4 as a catalyst.The synthesis was achieved by functional group elimination and formation of quinonic and hydroquinonic moieties. - Keywords: polyprenylbenzoquinol; polyprenylhydroquinone; allylcarbonate; ?-allyl palladium complex
Total synthesis of 2-tetraprenylbenzoquinol and -benzoquinone
Bouzbouz,Kirschleger
, p. 714 - 718 (2007/10/02)
The total synthesis of 2-tetraprenylbenzoquinol and -benzoquinone is described. A key step in this synthesis is the highly regio- and stereoselective coupling between an appropriate aromatic allylcarbonate and an activated bifunctional farnesyl derivative
