39719-02-3

Basic information

• Product Name: Benzoic acid, 4-methyl-, 2-phenylhydrazide
• CAS NO: 39719-02-3
• Molecular Formula: C14H14N2O
• Molecular Weight: 226.278
• Mol File: 39719-02-3.mol
• Article Data: 16

Chemical Properties

• CAS DataBase Reference: Benzoic acid, 4-methyl-, 2-phenylhydrazide(CAS DataBase Reference)
• NIST Chemistry Reference: Benzoic acid, 4-methyl-, 2-phenylhydrazide(39719-02-3)
• EPA Substance Registry System: Benzoic acid, 4-methyl-, 2-phenylhydrazide(39719-02-3)

Safety Data

• Hazardous Substances Data: 39719-02-3(Hazardous Substances Data)

Upstream product

• 64-17-5 ethanol 
• 30410-39-0 3-phenyl-1-(p-tolyl)-2,3-diazaprop-2-en-1-one 
• 26218-73-5 3,4-bis(4-methylphenyl)-1,2,5-oxadiazole-N-oxide 
• 100-63-0 phenylhydrazine 
• 7732-18-5 water 
• 99-94-5 p-Toluic acid 
• 59-88-1 phenylhydrazine hydrochloride 
• 59046-28-5 p-toluoyl-1H-1,2,3-benzotriazole 
• 2829-32-5 4-Methyl-benzylazo-benzo-α-hydroperoxyd 
• 36930-95-7 2,2,2-trichloro-1-(4-methylphenyl)ethanone 
• 79071-42-4 2,3-Diphenyl-5-p-tolyl-2,3-dihydro-[1,3,4]oxadiazole 
• 94-08-6 4-methylbenzoic acid ethyl ester 
• 874-60-2 4-methyl-benzoyl chloride 

Downstream Products

• 13756-42-8 tert-butyl 4-methylbenzoate 
• 49829-82-5 4-methyl-N',N'-diphenylbenzohydrazide 
• 3214-05-9 2-phenyl-5-(p-tolyl)-2,4-dihydro-3H-1,2,4-triazol-3-one 
• 33064-20-9 3-(4-methylphenyl)-1-phenyl-1H-pyrazole 
• 25939-01-9 4-methyl-N'-phenylbenzenecarbohydrazonoyl chloride 
• 25939-01-9 p-toluoyl chloride phenylhydrazone 

Relevant articles and documents

Synthesis of 3 H-1,2,4-Triazol-3-ones via NiCl2-Promoted Cascade Annulation of Hydrazonoyl Chlorides and Sodium Cyanate

A nickel-promoted cascade annulation reaction for the facile synthesis of 3H-1,2,4-triazol-3-ones from readily available hydrazonoyl chlorides and sodium cyanate has been developed. The transformation occurs through a cascade nickel-promoted intermolecular nucleophilic addition-elimination process, intramolecular nucleophilic addition, and a hydrogen-transfer sequence. The method has been successfully applied for the construction of the core skeleton of the angiotensin II antagonist.

A formal [3+2] cycloaddition reaction of: N -methylimidazole as a masked hydrogen cyanide: Access to 1,3-disubstitued-1 H -1,2,4-triazoles

N-Methylimidazole (NMI) can act as a masked HCN in the synthesis of 1,3-disubstitued-1H-1,2,4-triazoles via a formal cycloaddition reaction of hydrazonoyl chloride with NMI. The product was proved to be formed via an initial nucleophilic substitution of hydrazonoyl chloride with NMI following cyclization and two sequential C-N bond cleavages. This journal is

A [4 + 3] Annulation Reaction of aza- o-Quinone Methides with Arylcarbohydrazonoyl Chlorides for Synthesis of 2,3-Dihydro-1 H-benzo[ e][1,2,4]triazepines

An unprecedented [4 + 3] annulation reaction of aza-ortho-quinone methides with arylcarbohydrazonoyl chlorides has been achieved under mild conditions. The annulation underwent a sequential conjugate addition/intramolecular annulation/rearrangement, providing a useful method for the synthesis of biologically interesting 2,3-dihydro-1H-benzo[e][1,2,4]triazepine.