39720-18-8Relevant academic research and scientific papers
Chlorination and ortho-acetoxylation of 2-arylbenzoxazoles
Leng, Yuting,Yang, Fan,Zhu, Weiguo,Wu, Yangjie,Li, Xiang
, p. 5288 - 5296 (2011/08/05)
Efficient and facile catalytic protocols for chlorination and ligand-directed ortho-acetoxylation of 2-arylbenzoxazoles have been developed. The chlorination is not a ligand-directed ortho-functionalization, but an electrophilic substitution process in the benzo ring of the benzoxazole moiety. Meanwhile, the acetoxylation exhibited high regioselectivity for the substrates containing a meta-substituent and occurred at the less sterically hindered ortho-C-H bond of the directing group. The Royal Society of Chemistry 2011.
