3976-30-5

Basic information

• Product Name: N-[1-(4-chlorophenyl)ethyl]benzamide
• Synonyms: N-[1-(4-chlorophenyl)ethyl]benzamide
• CAS NO: 3976-30-5
• Molecular Weight: 259.735
• Mol File: 3976-30-5.mol
• Article Data: 7

Chemical Properties

• CAS DataBase Reference: N-[1-(4-chlorophenyl)ethyl]benzamide(CAS DataBase Reference)
• NIST Chemistry Reference: N-[1-(4-chlorophenyl)ethyl]benzamide(3976-30-5)
• EPA Substance Registry System: N-[1-(4-chlorophenyl)ethyl]benzamide(3976-30-5)

Safety Data

• Hazardous Substances Data: 3976-30-5(Hazardous Substances Data)

Upstream product

• 35588-60-4 p-chloro-(R,S)-1-phenylethylamine 
• 3391-10-4 1-(p-chlorophenyl)ethyl alcohol 
• 100-47-0 benzonitrile 
• 98-88-4 benzoyl chloride 
• 99-91-2 para-chloroacetophenone 
• 55-21-0 benzamide 
• 1073-67-2 4-vinylbenzyl chloride 
• 622-98-0 4-chloro(ethylbenzene) 

Relevant articles and documents

An efficient FeCl3-catalyzed amidation reaction of secondary benzylic and allylic alcohols with carboxamides or p-toluenesulfonamide

A simple, inexpensive, environmentally friendly and high yielding amidation reaction of benzylic and allylic alcohols with primary amides using a catalytic amount of FeCl3 (5 mol %) is described. Direct substitution of various amides such as be

Ritter reaction in subcritical water: An efficient and green method for amides synthesis

Ritter reaction was carried out efficiently in subcritical water with catalytic amount of trifluoromethanesulfonic acid. The amides were formed in good to excellent yields from secondary alcohols and tert-butanol with various nitriles.

Asymmetric synthesis of chiral primary amines by transfer hydrogenation of N -(tert -Butanesulfinyl)ketimines

(Figure presented) The diastereoselective reduction of (R)-N-(tert- butanesulfinyl)ketimines by a ruthenium-catalyzed asymmetric transfer hydrogenation process in isopropyl alcohol, followed by desulfinylation of the nitrogen atom, is an excellent method to prepare highly enantiomerically enriched α-branched primary amines (up to >99% ee) in short reaction times (1-4 h). (1S,2R)-1-Amino-2-indanol has been shown to be a very efficient ligand to perform this transformation. Ketimines bearing either an aryl or a heteroaryl group and an alkyl group as substituents of the iminic carbon atom are very good substrates for this process. The reduction of a dialkyl ketimine could also be achieved, affording the expected amine with moderate optical purity (69% ee). Some amines which are precursors of very interesting biologically and pharmacologically active compounds have been prepared in excellent yields and enantiomeric excesses.