39771-64-7Relevant academic research and scientific papers
Tetrahydroisoquinoline derivatives as melatonin MT2 receptor antagonists
Karageorge, George N.,Bertenshaw, Stephen,Iben, Lawrence,Xu, Cen,Sarbin, Nathan,Gentile, Anthony,Dubowchik, Gene M.
, p. 5881 - 5884 (2007/10/03)
A series of tetrahydroisoquinolines has yielded potent MT2 receptor antagonists, which are selective versus the MT1 receptor. A series of tetrahydroisoquinolines has yielded potent MT2 receptor antagonists, which are selective versus the MT1 receptor.
Tetrahydroisoquinoline derivatives as melatonin MT2 antagonists
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, (2008/06/13)
The invention encompasses a series of tetrahydroisoquinolines of formula I which are antagonists of the human melatonin MT2 receptor and are useful as chronobiotic and sleep agents.
