397842-91-0

Basic information

• Product Name: 1H-Pyrrolo[2,3-b]pyridine, 5-methoxy-2-methyl-
• Synonyms: 1H-Pyrrolo[2,3-b]pyridine, 5-methoxy-2-methyl-;5-Methoxy-2-methyl-1H-pyrrolo[2,3-b]pyridine
• CAS NO: 397842-91-0
• Molecular Formula: C9H10 N2 O
• Molecular Weight: 162.19
• Mol File: 397842-91-0.mol
• Article Data: 4

Chemical Properties

• Boiling Point: 324.321°C at 760 mmHg
• Flash Point: 110.818°C
• Appearance: /
• Density: 1.198g/cm³
• Vapor Pressure: 0mmHg at 25°C
• Refractive Index: 1.629
• CAS DataBase Reference: 1H-Pyrrolo[2,3-b]pyridine, 5-methoxy-2-methyl-(CAS DataBase Reference)
• NIST Chemistry Reference: 1H-Pyrrolo[2,3-b]pyridine, 5-methoxy-2-methyl-(397842-91-0)
• EPA Substance Registry System: 1H-Pyrrolo[2,3-b]pyridine, 5-methoxy-2-methyl-(397842-91-0)

Safety Data

• Hazardous Substances Data: 397842-91-0(Hazardous Substances Data)

Usage

Type of compound

Heterocyclic aromatic compound

Core structure

Pyrrolopyridine

Substituents

Methoxy and methyl groups

Common uses

Building block for the synthesis of biologically active compounds, potential drug candidates, research and development as a precursor for the synthesis of new chemical entities

Potential therapeutic properties

Under investigation for potential applications in the treatment of various diseases

Importance

Diverse potential applications in the fields of medicine and chemistry

InChI:InChI=1/C9H10N2O/c1-6-3-7-4-8(12-2)5-10-9(7)11-6/h3-5H,1-2H3,(H,10,11)

Upstream product

• 651744-20-6 5-methoxy-2-methyl-1-tosyl-1H-pyrrolo[2,3-b]pyridine 
• 1383924-92-2 5-methoxy-1-(p-tolylsulfonyl)pyrrolo[2,3-b]pyridine 
• 183208-35-7 5-bromo-1H-pyrrolo[2,3-b]pyridine 
• 183208-36-8 5-methoxy-1H-pyrrolo[2,3-b]pyridine 

Relevant articles and documents

FAAH INHIBITORS

The present disclosure relates to compounds useful as inhibitors of the enzyme Fatty Acid Amide Hydrolase (FAAH). The disclosure also provides pharmaceutically acceptable compositions comprising the compounds of the disclosure and methods of using the com

Quinoline derivatives having vegf inhibiting activity

The invention relates to compounds of formula (I) wherein: either any one of G1, G2, G3, G4 and G5 is nitrogen and the other four are —CH—, or G1, G2, G3, G4 and G5 are all —CH—; Z is —O—, —NH—, —S—, —CH2— or a direct bond; Z is linked to any one of G1, G2, G3 and G4; n is an integer from 0 to 5; m is an integer from 0 to 3; Ra represents hydrogen or fluoro; Rb, R1 and R2 are defined herein and salt thereof, process for the preparation so such compounds, pharmaceutical compositions containing a compound of formula I or a pharmaceutically acceptable salt thereof as active ingredient and the use of a compound of formula I in the manufacture of a medicament for the production of an antiangiogenic and/or vascular permeability reducing effect in warm-blodded animals. The compounds of formula I and the pharmaceutically acceptable salts thereof inhibit the effects of VEGF, a property of value in the treatment of a number of diseases states including cancer and rheumatoid arthritis.