397845-44-2

Upstream product

• 117-12-4 1,5-dihydroxyanthraquinone 
• 100-39-0 benzyl bromide 

Downstream Products

• 117-12-4 1,5-dihydroxyanthraquinone 
• 1224695-91-3 1-(benzyloxy)-5-hydroxyanthracene-9,10-dione 
• 1224695-94-6 1-benzoyl-5-(benzyloxy)anthracene-9,10-dione 
• 1224695-96-8 10-benzyl-5-(benzyloxy)-1,10-dihydroxyanthracen-9(10H)-one 
• 1224695-98-0 1-benzyl-5-(benzyloxy)-1-hydroxyanthracene-9,10-dione 

Relevant academic research and scientific papers

COMPOUNDS AND METHODS OF TREATING RNA-MEDIATED DISEASES

The present invention provides compounds, compositions thereof, and methods of using the same.

Microemulsion Topical Delivery Platform

Provided are pharmaceutical carriers suitable based on oil-in-water microemulsions and methods of making same. Also provided are pharmaceutical compositions comprising a carrier of the invention and a lipophilic active pharmaceutical ingredient (API), as well as methods for making same. The pharmaceutical compositions are particularly suitable for use in formulating lipophilic APIs for topical administration to the eye. Specifically included are pharmaceutical compositions comprising fenofibrate or fenofibric acid as API. Also provided is a method of treating a disease of the posterior segment of the eye. Also provided is a pharmaceutical composition comprising a compound represented by formulated for topical administration to the eye.

Photochemistry of 1, n -Dibenzyloxy-9,10-anthraquinones

Figure presented The photochemistry of a series of 9,10-anthraquinones with multiple benzyloxy substituents was investigated. In polar solvent, the expected Blankespoor oxidative cleavage reaction is the major reaction pathway, but in most cases, several minor products were observed. In nonpolar solvents, the abundance of these minor products increases dramatically. Four types of product were observed with the favored reaction pathway shifting with minor changes in substitution on the anthraquinone. Several types of product require cleavage of the C-O bond on the benzyloxy group and, apparently, follow a photo-Claisen-type mechanism. Others involve the expected 1,5-diradical but do not exhibit the single-electron transfer usually observed in the Blankespoor-type reaction. The results indicate the importance of considering the medium and photoredox behavior in anthraquinone photochemistry.