39802-47-6Relevant academic research and scientific papers
Thermodynamic and structural effects of conformational constraints in protein-ligand interactions. Entropic paradoxy associated with ligand preorganization
DeLorbe, John E.,Clements, John H.,Teresk, Martin G.,Benfield, Aaron P.,Plake, Hilary R.,Millspaugh, Laura E.,Martin, Stephen F.
supporting information; experimental part, p. 16758 - 16770 (2010/03/04)
Succinate- and cyclopropane-derived phosphotyrosine (pY) replacements were incorporated into a series of Grb2 SH2 binding ligands wherein the pY+1 residue was varied to determine explicitly how variations in ligand preorganization affect binding energetic
Peptide Synthesis in Alcohol Solvents by the Mixed Anhydride Method Using Dimethylphosphinothioyl Chloride
Ueki, Masaaki,Saito, Takashi,Sasaya, Jun,Ikeda, Shigeru,Oyamada, Hidekazu
, p. 3653 - 3658 (2007/10/02)
The formation and coupling of the dimethylphosphinothioic mixed anhydrides of protected amino acids can be performed in alcohol solvents.Sparingly soluble protected C-terminal segments of vasoactive intestinal peptide (VIP) up to the heptapeptide stage we
