398133-30-7

Upstream product

• 77-78-1 dimethyl sulfate 
• 398133-29-4 (2R,4R)-(-)-4-tert-butyldiphenylsilyloxymethyl-2-fluoro-γ-butyrolactone 
• 212954-52-4 (R)-5-(tert-Butyl-diphenyl-silanyloxymethyl)-3-fluoro-5H-furan-2-one 

Downstream Products

• 398133-31-8 (2R,4R)-4-Acetylsulfanyl-5-(tert-butyl-diphenyl-silanyloxy)-2-fluoro-pentanoic acid methyl ester 
• 398133-35-2 (-)-N⁴-benzoyl-1-[(1S,2S,4R)-5-O-(tert-butyldiphenylsilyl)-2,3-dideoxy-2-fluoro-2-phenylselenyl-4-thio-β-L-ribofuranosyl]cytosine 
• 398133-36-3 (+)-N⁴-benzoyl-1-[(1S,4R)-5-O-(tert-butyldiphenylsilyl)-2,3-dideoxy-2,3-didehydro-2-fluoro-4-thio-β-L-ribofuranosyl]cytosine 
• 398133-34-1 (1S/R,2S,4R)-1-O-aceyl-5-O-(tert-butyldiphenylsilyl)-2,3-dideoxy-2-fluoro-2-phenylselenyl-4-thio-β-L-ribofuranoside 
• 398133-33-0 (2S,4R)-(-)-4-tert-butyldiphenylsilyloxymethyl-2-fluoro-2-phenylselenyl-γ-thiobutyrolactone 
• 398133-32-9 (2R,4R)-(-)-4-tert-butyldiphenylsilyloxymethyl-2-fluoro-γ-thiobutyrolactone 

Relevant academic research and scientific papers

Synthesis and potent anti-HIV activity of L-2',3'-didehydro-2',3'-dideoxy-2'-fluoro-4'-thiocytidine.

[reaction: see text] L-2'-Fluoro-4'-thio-2',3'-unsaturated cytidine 11 was synthesized from (R)-2-fluorobutenolide 2, which was prepared from 2,3-O-isopropylidene-L-glyceraldehyde 1. The synthesized compound 11 shows potent antiviral activity against HIV-