398143-07-2

Upstream product

• 171013-46-0 3,5-dimethoxy-2-hydroxy-4-methyl benzyl alcohol 
• 271578-82-6 1-((R)-1-Azido-2-benzyloxy-ethyl)-2,3,5-trimethoxy-4-methyl-benzene 
• 271578-81-5 (R)-2-Azido-2-(2,3,5-trimethoxy-4-methyl-phenyl)-ethanol 
• 271578-79-1 (S)-1-(2,3,5-Trimethoxy-4-methyl-phenyl)-ethane-1,2-diol 
• 271578-80-4 (S)-2-(2,3,5-Trimethoxy-4-methyl-phenyl)-oxirane 
• 85071-59-6 1-bromo-2,3,5-trimethoxy-4-methylbenzaldehyde 
• 100-39-0 benzyl bromide 
• 271578-78-0 1,3,4-trimethoxy-2-methyl-5-vinylbenzene 
• 271578-83-7 [2-benzyloxy-1-(2,3,5-trimethoxy-4-methyl-phenyl)-ethyl]-carbamic acid tert-butyl ester 

Downstream Products

• 271578-84-8 [(R)-2-Benzyloxy-1-(2,3,5-trimethoxy-4-methyl-phenyl)-ethyl]-(2,2-diethoxy-ethyl)-amine 
• 398142-93-3 1-benzyloxymethyl-4-hydroxy-5,7,8-trimethoxy-6-methyl-3,4-dihydro-1H-isoquinoline-2-carboxylic acid tert-butyl ester 
• 271578-85-9 (R)-1-Benzyloxymethyl-5,7,8-trimethoxy-6-methyl-1,2,3,4-tetrahydro-isoquinolin-4-ol 

Relevant academic research and scientific papers

Studies directed to the total synthesis of ET 743 and analogues thereof: An expeditious route to the ABFGH subunit

(matrix presented) In model studies directed to the total synthesis of Et743, a strategic S-C bond formation in systems 26 and 27 was demonstrated. It was further shown that Pictet-Spengler cyclization leading to spiro product 33 exhibits very high stereo

Synthetic explorations in the saframycin-ecteinascidin series: Construction of major chiral subunits through catalytic asymmetric induction

The major subunits needed to reach the titled targets have been assembled by chemistry, which included p-Claisen rearrangement, asymmetric epoxidation and asymmetric dihydroxylation. (C) 2000 Elsevier Science Ltd.