3982-42-1

Basic information

• Product Name: 2,2′-Bis(4-methylbenzolsulfonylamido)-diphenyldisulfid
• Synonyms: 2,2′-Bis(4-methylbenzolsulfonylamido)-diphenyldisulfid
• CAS NO: 3982-42-1
• Molecular Formula: C₂₆H₂₄N₂O₄S₄
• Molecular Weight: 556.73976
• Mol File: 3982-42-1.mol
• Article Data: 3

Chemical Properties

• Boiling Point: 685.2°Cat760mmHg
• Flash Point: 368.2°C
• Appearance: /
• Density: 1.46g/cm³
• CAS DataBase Reference: 2,2′-Bis(4-methylbenzolsulfonylamido)-diphenyldisulfid(CAS DataBase Reference)
• NIST Chemistry Reference: 2,2′-Bis(4-methylbenzolsulfonylamido)-diphenyldisulfid(3982-42-1)
• EPA Substance Registry System: 2,2′-Bis(4-methylbenzolsulfonylamido)-diphenyldisulfid(3982-42-1)

Safety Data

• Hazardous Substances Data: 3982-42-1(Hazardous Substances Data)

Usage

General Description

2,2′-Bis(4-methylbenzolsulfonylamido)-diphenyldisulfid, also known as MBSD, is a chemical compound with the molecular formula C30H28N2O4S2. It is a yellowish-brown powder that is insoluble in water but soluble in organic solvents. MBSD is commonly used as a rubber vulcanization accelerator, as well as in the production of cross-linked rubber products. It is also employed as a curing agent in the production of epoxy resins. Additionally, MBSD has potential applications in the field of organic synthesis and material science due to its versatile chemical properties. However, it is important to handle MBSD with care, as prolonged exposure can cause irritation and harmful effects on human health.

Upstream product

• 106950-44-1 dithiodianiline 
• 98-59-9 p-toluenesulfonyl chloride 
• 104-15-4 toluene-4-sulfonic acid 
• 1141-88-4 2-Aminophenyl disulfide 
• 137-07-5 2-amino-benzenethiol 

Downstream Products

• 60512-85-8 (E)-isopropyl cinnamate 
• 29476-22-0 (R)-2-phenyl-2,3-dihydrobenzo[b][1,4]thiazepin-4(5H)-one 
• 55423-98-8 N-(2-mercaptophenyl)-4-methylbenzenesulfonamide 

Relevant articles and documents

Preparation method for 2,2'-di(4-methyl benzene sulfoamino)diphenyl disulphide

The invention discloses a preparation method for 2,2'-di(4-methyl benzene sulfoamino)diphenyl disulphide as rubber peptizer. According to the method, 2,2'-diaminodiphenyl disulfide, N,N'-diisopropylcarbodiimide, N-methylmorpholine and tetrahydrofuran are placed in a round-bottom flask; stirring is started, and a tetrahydrofuran solution of p-toluene sulfonic acid is slowly dropped, wherein the reaction time is 20 h to 40 h; and after a reaction is finished, a product is obtained after a mixture is filtrated, washed and dried. The Mooney viscosity value of plasticated rubber of the peptizer is 62.7. The method has the technical beneficial effects that the reaction process is simple, the purity of the obtained product is high, and after-treatment is simple.

Facile net cycloaddition approach to optically active 1,5-benzothiazepines

The 1,5-benzothiazepine moiety is well-known as a versatile pharmacophore, and its derivatives are expected to have antagonism against numerous diseases. Thus, it is desirable to develop a synthetic route that enables facile enantioselective preparation of a wide range of such derivatives. Although the cycloaddition approach could be considered a possible route to these compounds, to date, there has been no precedent of such a protocol. We therefore present the first example of a highly enantioselective net [4 + 3] cycloaddition to afford 1,5-benzothiazepines by utilizing α,β-unsaturated acylammonium intermediates generated by chiral isothiourea catalysts, which undergo two sequential chemoselective nucleophilic attacks by 2-aminothiophenols. This protocol provided cycloadducts in extremely high regioselectivity, with a good-to-excellent stereoselectivity being achieved regardless of the steric and electronic properties of the substrates. This method therefore offers promising synthetic routes for the construction of a library of optically active 1,5-benzothiazepines for assay evaluation.