39830-76-7Relevant academic research and scientific papers
Design, synthesis and characterization of functionalized pyrazole derivatives bearing amide and sulfonamide moieties from aza-aurones
Akhazzane, Mohamed,Al Houari, Ghali,Bakhouch, Mohamed,Bourass, Mohamed,Chalkha, Mohammed,El Yazidi, Mohamed,Nicolas, Yohann
, (2020/07/17)
Abstract: In this work, we report the synthesis of new pyrazole derivatives bearing amide and sulfonamide frameworks from aza-aurones. Firstly, the intermediate spiropyrazolines were obtained through a highly regioselective 1,3-dipolar cycloaddition of nitrilimines with aza-aurones. Subsequently, the obtained cycloadducts were subjected to hydrochloric acid in hot ethanol which conducts to 5-(2-aminobenzoyl)-3,4-diaryl-1-phenylpyrazoles. Finally, the target compounds were obtained separately by the action of acetic anhydride, benzoyl chloride and tosyl chloride on the intermediates 2-aminobenzoylpyrazoles, respectively. Structures of all the synthesized compounds were established using IR, 1H NMR and 13C NMR and mass spectroscopy. Graphic Abstract: Synthesis and characterization of novel heterocyclic systems encompassing pyrazole derivatives from aza-aurones are reported. The synthetic routes used in this work are efficient and relevant, involving the 1,3-dipolar cycloaddition and alkylation reactions. The outcomes show that spectroscopic data fit the structure of all synthesized compounds.[Figure not available: see fulltext.]
A general and convenient palladium-catalyzed synthesis of benzylideneindolin-3-ones with formic acid as the CO source
Li, Rui,Qi, Xinxin,Wu, Xiao-Feng
supporting information, p. 6905 - 6908 (2017/09/01)
A general and convenient palladium-catalyzed carbonylative synthesis of 2-benzylideneindolin-3-ones from 2-iodoanilines and arylacetylenes has been developed. With formic acid as the CO source and Ac2O as the activator, a variety of 2-benzylideneindolin-3-ones were obtained in good to excellent yields with exceptional functional group tolerance.
Color and Constitution. Part 8 . Some Novel Dyestuffs Containing Indoxyl Residues
Katritzky, Alan R.,Li, Qiao-Ling,Fan, Wei-Qiang
, p. 1287 - 1292 (2007/10/02)
Novel dyes containing C-linked indoxyl residues are prepared by two routes: (a) by the reaction of C-electrophiles with N-acetylindoxyl and (b) by the reaction of active methylene compounds with 2-chloroindole-3-one.The visible absorption spectra are recorded and discussed.
