39835-28-4

Usage

Uses

Used in Pharmaceutical Industry:
5-NITRO-1,2-BENZISOXAZOLE is used as a key intermediate in the synthesis of various pharmaceuticals and organic compounds. Its unique chemical structure and properties contribute to the development of new drugs with potential therapeutic applications.
Used in Antimicrobial Applications:
5-NITRO-1,2-BENZISOXAZOLE is used as an antimicrobial agent due to its ability to inhibit the growth of certain microorganisms. Its effectiveness in combating bacterial and fungal infections makes it a valuable component in the development of new antimicrobial drugs.
Used in Antiviral Applications:
5-NITRO-1,2-BENZISOXAZOLE is used as an antiviral agent, exhibiting potential activity against specific viruses. Its antiviral properties can be harnessed in the development of new treatments for viral infections, offering an alternative to existing antiviral medications.
Used in Chemical Research:
5-NITRO-1,2-BENZISOXAZOLE is used as a research compound in various scientific studies. Its unique properties and reactivity make it a valuable tool for understanding chemical reactions and exploring new synthetic pathways in organic chemistry.

InChI:InChI=1/C7H4N2O3/c10-9(11)6-1-2-7-5(3-6)4-8-12-7/h1-4H

Upstream product

• 97-51-8 5-Nitrosalicylaldehyde 
• 1595-15-9 2-hydroxy-5-nitro-benzaldehyde oxime 
• 271-95-4 1,2-benzisoxazole 

Downstream Products

• 39835-09-1 5-nitro-2-hydroxybenzonitrile 
• 39835-14-8 2-hydroxy-4-nitro-benzonitrile 
• 239097-74-6 benzo[d]-isoxazol-5-amine 
• 16331-61-6 5-Nitro-N-ethyl-salicylamid 

Relevant academic research and scientific papers

Interconnectivity between Surface Reactivity and Self-Assembly of Kemp Elimination Catalyzing Nanorods

Understanding the fundamental facts behind dynamicity of catalytic processes has been a longstanding quest across disciplines. Herein, we report self-assembly of catalytically active gold nanorods that can be regulated by tuning its reactivity towards a p

[3 + 2]-Cycloaddition of Azaoxyallyl Cations with 1,2-Benzisoxazoles: A Rapid Entry to Oxazolines

A novel and efficient [3 + 2] cycloaddition reaction of azaoxyallyl cations and 1,2-benzisoxazoles to give oxazoline derivatives has been developed. The transformation provides a rapid entry to functionalized oxazoline scaffolds under mild and transition-metal-free conditions, which will greatly expand the reaction types of heterocycle chemistry and pave the way for syntheses of bioactive compounds.

Utility of Nitrogen Extrusion of Azido Complexes for the Synthesis of Nitriles, Benzoxazoles, and Benzisoxazoles

The utility of the nitrogen extrusion reaction of azido complexes, generated in situ from the corresponding aldehydes or ketones with TMSN3 in the presence of ZrCl4 or TfOH, has been described. These azido complexes could undergo three different pathways, depending on the substrates. First, azido methanolate complexes or imine diazonium ions could lead to benzisoxazole products via an intramolecular nucleophilic substitution. Second, imine diazonium ions could also undergo either the elimination of proton to provide nitrile products in good to excellent yields or an aryl migration, followed by an intramolecular nucleophilic addition, to give benzoxazole products in good yields.

4-Piperidinecarboxamide modulators of vanilloid VR1 receptor

This invention is directed to vanilloid receptor VR1 ligands. More particularly, this invention relates to hetero isonipecotic amides that are potent modulators of VR1 which are useful for the treatment and prevention of disease conditions in mammals.

Bacterial siderophores: Synthesis and biological activities of novel pyochelin analogues

The synthesis and biological activities of four pyochelin analogues substituted in different parts of the molecule are reported: 5-NHBoc-pyochelin, 3″N-Boc-pyochelin, 3″-nor-NH-pyochelin and neopyochelin II, the enantiomer of natural pyochelin. All these

Characterization of proton-transfer catalysis by serum albumins

Two independent investigations of catalysis by BSA and other serum albumins are combined to provide detailed insight into the mechanism of a classical proton-transfer reaction taking place on the surface of a protein. The Kemp elimination involves the gen