39835-09-1

Usage

Uses

Used in Pharmaceutical Industry:
2-Hydroxy-5-nitrobenzonitrile is used as an intermediate in the synthesis of various pharmaceuticals for its reactivity and ability to form diverse chemical structures.
Used in Organic Compounds Synthesis:
It serves as a building block for the synthesis of various organic compounds, leveraging its reactive functional groups to create a wide range of products.
Used in Agrochemical Industry:
2-Hydroxy-5-nitrobenzonitrile is utilized in the synthesis of heterocyclic compounds, which have applications in the agrochemical industry for their potential use in developing new pesticides or other agrochemical products.
Used in Dyes and Pigments Production:
Due to its vibrant yellow color, 2-Hydroxy-5-nitrobenzonitrile is used in the production of dyes and pigments, contributing to the coloration of various materials.
Safety Precautions:
It is important to handle 2-Hydroxy-5-nitrobenzonitrile with care, as it may be harmful if ingested or inhaled and can cause irritation to the skin and eyes. Proper safety measures should be taken during its use and disposal to minimize potential health risks.

Upstream product

• 39835-28-4 5-Nitro-benzo[d]isoxazole 
• 89692-57-9 6-chloro-3-nitro-benzaldehyde-(Z)-oxime 
• 89692-57-9 6-chloro-3-nitro-benzaldehyde-(E)-oxime 
• 28691-51-2 3-carboxy-5-nitro-1,2-benzisoxazole 
• 463-71-8 thiophosgene 
• 16588-02-6 4-chloro-3-cyanonitrobenzene 
• 611-20-1 salicylonitrile 
• 7697-37-2 nitric acid 
• 97-51-8 5-Nitrosalicylaldehyde 
• 6361-21-3 2-chloro-5-nitrobenzaldehyde 
• 1595-15-9 2-hydroxy-5-nitro-benzaldehyde oxime 
• 70886-33-8 5-nitro-benzooxazole 
• 64-19-7 acetic acid 
• 10199-89-0 NBD chloride 

Downstream Products

• 105430-53-3 5-amino-2-hydroxybenzonitrile hydrochloride 
• 883455-48-9 (3-cyano-4-hydroxyphenyl)carbamic acid 2-trimethylsilylethyl ester 
• 10496-75-0 2-methoxy-5-nitrobenzylnitrile 
• 82245-67-8 5-nitro-2-propoxybenzonitrile 
• 288252-06-2 2-cyclohexyloxy-5-nitro-benzonitrile 

Relevant academic research and scientific papers

Interconnectivity between Surface Reactivity and Self-Assembly of Kemp Elimination Catalyzing Nanorods

Understanding the fundamental facts behind dynamicity of catalytic processes has been a longstanding quest across disciplines. Herein, we report self-assembly of catalytically active gold nanorods that can be regulated by tuning its reactivity towards a p

Catalysis of the Kemp elimination by antibodies elicited against a cationic hapten

Rather efficient catalysis of the decomposition of 5-nitro-benzisoxazole to the cyanophenol was observed with antibodies elicited against a cationic hapten structurally unrelated to the benzisoxazole substrate. The rate enhancement by the most active anti

Vesicles accelerate proton transfer from carbon up to 850-fold

(equation presented) We have analyzed the different catalytic effects of surfactant aggregates upon the rate-determining hydroxide ion induced deprotonation reaction of 1. Vesicles are more effective catalysts than micelles, most likely providing a more a

Superior Proton-Transfer Catalytic Promiscuity of Cytochrome c in Self-Organized Media

Evolutionarily elderly proteins commonly feature greater catalytic promiscuity. Cytochrome c is among the first set of proteins in evolution to have known prospects in electron transport and peroxidative properties. Here, we report that cyt c is also a pr

Investigation of medium effects in a family of decarboxylase antibodies

A family of naphthalenedisulfonate-binding antibodies catalyze the decarboxylation of 5-nitro-3-carboxybenzisoxazole, providing a series of structurally similar catalysts for investigating the influence of protein microenvironment on reactivity. Eight rep

Mechanistic study of proton transfer and hysteresis in catalytic antibody 16E7 by site-directed mutagenesis and homology modeling

Antibody 16E7 catalyzes the carbon protonation of enol ether 2 to hemiacetal 3, and the carbon deprotonation of benzisoxazole 7 to phenol 8. This antibody shows an extreme case of hysteresis, requiring several hours to reach full activity. Antibody 16E7 w

Design of a switchable eliminase

The active sites of enzymes are lined with side chains whose dynamic, geometric, and chemical properties have been finely tuned relative to the corresponding residues in water. For example, the carboxylates of glutamate and aspartate are weakly basic in w

Characterization of proton-transfer catalysis by serum albumins

Two independent investigations of catalysis by BSA and other serum albumins are combined to provide detailed insight into the mechanism of a classical proton-transfer reaction taking place on the surface of a protein. The Kemp elimination involves the gen

Catalysis of the Kemp elimination by natural coals

(matrix presented) Commercially available coals were found to be efficient heterogeneous catalysts of the Kemp elimination reaction in aqueous solutions. A pH-rate profile study suggests that catalysis originates from specific catalytic groups and not sim

Influence of water-soluble pillararene hosts on Kemp elimination

Since pillar[5]arene was first discovered in 2008, it has developed into a multifunctional supramolecular host. Its application covers many fields from drug delivery and chemical sensing to the construction of molecular machines, and so on. Supramolecular