398469-82-4

Basic information

• Product Name: 1,3-bis(5-thio-β-D-galactopyranosyldisulfanylmethyl)-5-methanethiosulfonatomethyl-2,4,6-trimethylbenzene
• Synonyms: 1,3-bis(5-thio-β-D-galactopyranosyldisulfanylmethyl)-5-methanethiosulfonatomethyl-2,4,6-trimethylbenzene
• CAS NO: 398469-82-4
• Molecular Weight: 724.981
• Mol File: 398469-82-4.mol

Chemical Properties

• CAS DataBase Reference: 1,3-bis(5-thio-β-D-galactopyranosyldisulfanylmethyl)-5-methanethiosulfonatomethyl-2,4,6-trimethylbenzene(CAS DataBase Reference)
• NIST Chemistry Reference: 1,3-bis(5-thio-β-D-galactopyranosyldisulfanylmethyl)-5-methanethiosulfonatomethyl-2,4,6-trimethylbenzene(398469-82-4)
• EPA Substance Registry System: 1,3-bis(5-thio-β-D-galactopyranosyldisulfanylmethyl)-5-methanethiosulfonatomethyl-2,4,6-trimethylbenzene(398469-82-4)

Safety Data

• Hazardous Substances Data: 398469-82-4(Hazardous Substances Data)

Upstream product

• 42891-22-5 1-thio-β-D-galactose (Na⁺-form) 
• 398469-77-7 1,3,5-tris(methanethiosulfonatomethyl)-2,4,6-trimethylbenzene 
• 21988-87-4 1,3,5-tris(bromomethyl)-2,4,6-trimethylbenzene 

Relevant articles and documents

SYNTHESIS AND USE OF GLYCODENDRIMER REAGENTS

The present invention relates to a chemically modified mutant protein including a cysteine residue substituted for a residue other than cysteine n a precursor protein, the substituted cysteine residue being subsequently modified by reacting the cysteine residue with a glycosylated thiosulfonate. Also a method of producing the chemically modified mutant protein is provided. The present invention also relates to a glycosylated methanethiosulfonate. Another aspect of the present invention is a method of modifying the functional characteristics of a protein including providing a protein and reacting the protein with a glycosylated methanethiosulfonate reagent under conditions effective to produce a glycoprotein with altered functional characteristics as compared to the protein. In addition, the present invention relates to methods of determining the structure-function relationships of chemically modified mutant proteins. The present invention also relates to synthetic methods for producing thio-glycoses, the thio-glycoses so produced, and to methods for producing glycodendrimer reagents.

Glycodendriproteins: A Synthetic Glycoprotein Mimic Enzyme with Branched Sugar-Display Potently Inhibits Bacterial Aggregation

The continuing ability of bacteria to resist current antibiotic treatments highlights the need for alternative strategies for inhibiting their pathogenicity. Bacterial attachment is a major factor in infectivity and virulence. This key binding phase of ba