398476-19-2

Upstream product

• 398476-16-9 (3R, 5R, 10R)-10-(tert-butoxycarbonylmethyl)-7-(4-methoxybenzyl)-1,6-dioxa-2,7-diaza-spiro[4,5]decane-2,3-dicarboxylic 2-tert-butyl ester 3-methyl ester 
• 398476-15-8 (3rac, 5R)-1-(tert-butoxycarbonyl)-3-{[(N-tert-butoxycarbonyl)-N-(4-methoxybenzyl)but-3-yn-1-yl]carbamoyl}-2-pyrrolidinon-5-carboxylic methyl ester 
• 398476-17-0 (3R, 5S, 10R)-10-(tert-butoxycarbonylmethyl)-7-(4-methoxybenzyl)-1,6-dioxa-2,7-diaza-spiro[4,5]decane-3-carboxylic methyl ester 
• 398476-12-5 N-(tert-butoxycarbonyl)-N-(4-methoxybenzyl)-5-amino-1-pent-2-ynoic tert-butyl ester 
• 398476-14-7 (3rac, 5R)-1-(tert-butoxycarbonyl)-3-(thioethoxycarbonyl)-2-pyrrolidinon-5-carboxylic methyl ester 
• 398476-24-9 N-(tert-butoxycarbonyl)-N-(4-methoxybenzyl)-4-amino-1-butyne 
• 398476-13-6 N-(4-methoxybenzyl)-5-amino-1-pent-2-ynoic tert-butyl ester 
• 146980-79-2 N-(4-methoxybenzyl)-4-amino-1-butyne 
• 128811-48-3 1‐(tert‐butyl) 2‐methyl (R)‐5‐oxopyrrolidine‐1,2‐dicarboxylate 
• 398476-18-1 (3R, 5S, 10R)-10-(tert-butoxycarbonylmethyl)-3-(2-hydroxymethyl)-7-(4-methoxybenzyl)-1,6-dioxa-2,7-diaza-spiro[4,5]decane 

Downstream Products

• 398476-20-5 (3R, 5S, 10R)-10-(tert-butoxycarbonylmethyl)-7-(4-methoxybenzyl)-3-vinyl-1,6-dioxa-2,7-diaza-spiro[4,5]decane 
• 398476-21-6 (3R, 5S, 10R)-10-(tert-butoxycarbonylmethyl)-2-(5-hexenyl)-7-(4-methoxybenzyl)-3-vinyl-1,6-dioxa-2,7-diaza-spiro[4,5]decane 

Relevant academic research and scientific papers

Indenylidene complexes of ruthenium: Optimized synthesis, structure elucidation, and performance as catalysts for Olefin metathesis - Application to the synthesis of the ADE-ring system of nakadomarin A

An optimized and large scale adaptable synthesis of the ruthenium phenylindenylidene complex 3 is described which employs commercially available diphenyl propargyl alcohol 5 as a stable and convenient carbene source. Previous ambiguities as to the actual