398476-24-9

Upstream product

• 24424-99-5 di-tert-butyl dicarbonate 
• 146980-79-2 N-(4-methoxybenzyl)-4-amino-1-butyne 
• 1179838-41-5 (+/-)-1-(4-methoxybenzyl)azetidine-2-carbonitrile 
• 2393-23-9 4-methoxy-benzylamine 

Downstream Products

• 398476-13-6 N-(4-methoxybenzyl)-5-amino-1-pent-2-ynoic tert-butyl ester 
• 398476-20-5 (3R, 5S, 10R)-10-(tert-butoxycarbonylmethyl)-7-(4-methoxybenzyl)-3-vinyl-1,6-dioxa-2,7-diaza-spiro[4,5]decane 
• 398476-19-2 (3R, 5S, 10R)-10-(tert-butoxycarbonylmethyl)-7-(4-methoxybenzyl)-1,6-dioxa-2,7-diaza-spiro[4,5]decane-3-carboxaldehyde 
• 398476-18-1 (3R, 5S, 10R)-10-(tert-butoxycarbonylmethyl)-3-(2-hydroxymethyl)-7-(4-methoxybenzyl)-1,6-dioxa-2,7-diaza-spiro[4,5]decane 
• 398476-17-0 (3R, 5S, 10R)-10-(tert-butoxycarbonylmethyl)-7-(4-methoxybenzyl)-1,6-dioxa-2,7-diaza-spiro[4,5]decane-3-carboxylic methyl ester 
• 398476-15-8 (3rac, 5R)-1-(tert-butoxycarbonyl)-3-{[(N-tert-butoxycarbonyl)-N-(4-methoxybenzyl)but-3-yn-1-yl]carbamoyl}-2-pyrrolidinon-5-carboxylic methyl ester 
• 398476-16-9 (3R, 5R, 10R)-10-(tert-butoxycarbonylmethyl)-7-(4-methoxybenzyl)-1,6-dioxa-2,7-diaza-spiro[4,5]decane-2,3-dicarboxylic 2-tert-butyl ester 3-methyl ester 
• 398476-21-6 (3R, 5S, 10R)-10-(tert-butoxycarbonylmethyl)-2-(5-hexenyl)-7-(4-methoxybenzyl)-3-vinyl-1,6-dioxa-2,7-diaza-spiro[4,5]decane 
• 1438394-20-7 C₁₈H₂₅NO₃ 
• 1438394-33-2 N-(4-methoxybenzyl)-1-oxo-N-(penta-3,4-dien-1-yl)indane-2-carboxamide 
• 1438394-22-9 C₁₃H₁₇NO 
• 1438394-64-9 C₃₁H₃₁NO₃ 
• 398476-12-5 N-(tert-butoxycarbonyl)-N-(4-methoxybenzyl)-5-amino-1-pent-2-ynoic tert-butyl ester 

Relevant academic research and scientific papers

Indenylidene complexes of ruthenium: Optimized synthesis, structure elucidation, and performance as catalysts for Olefin metathesis - Application to the synthesis of the ADE-ring system of nakadomarin A

An optimized and large scale adaptable synthesis of the ruthenium phenylindenylidene complex 3 is described which employs commercially available diphenyl propargyl alcohol 5 as a stable and convenient carbene source. Previous ambiguities as to the actual

Synthesis of homopropargylamines from 2-cyanoazetidines

2-Cyanoazetidines, easily accessible from β-amino alcohols, undergo ring-cleavage upon reaction with trimethylsilylazide and catalytic amounts of Bu2SnO, to give the corresponding homopropargylamines which are isolated as their N-Boc protected

Enantio- and diastereoselective palladium catalysed arylative and vinylative allene carbocyclisation cascades

The enantioselective synthesis of heavily decorated spirolactams has been accomplished via an arylative or vinylative allene carbocyclisation cascade. Mediated by silver phosphate, a range of allene-linked pro-nucleophiles and aryl or vinyl iodides were reacted in the presence of catalytic Pd(OAc)2 and chiral bis(oxazoline) ligands to afford the spirolactam products in good yields and high enantio- and diastereoselectivities. The Royal Society of Chemistry 2013.