39870-17-2Relevant academic research and scientific papers
Copper-Catalyzed Synthesis of N-Formyl/Acylsulfenamides and -thiosulfonamides
Lee, Chan,Lim, Yu Na,Jang, Hye-Young
, p. 5934 - 5938 (2015)
Recent remarkable success of copper-catalyzed oxidative bond formations led us to develop an environmentally benign copper-catalyzed sulfur-nitrogen bond-forming reaction to provide synthetically and industrially useful electron-deficient sulfenamides. The low nucleophilicity of N-formyl/acyl- and sulfonylamides was overcome by introducing a 1,5,7-triazabicyclo[4.4.0]dec-5-ene additive. A variety of N-formyl/acylsulfenamides and -thiosulfonamides were synthesized in good yields without over-oxidation of sulfur. Related mechanistic studies supported the proposed reaction mechanism.
Synthesis of N-acylsulfenamides through aerobic cross dehydrogenative coupling of thiols and amides by supported copper hydroxide catalyst
Sakagami, Konomi,Jin, Xiongjie,Suzuki, Kosuke,Yamaguchi, Kazuya,Mizuno, Noritaka
, p. 173 - 175 (2016)
In the presence of a supported copper hydroxide catalyst Cu(OH)x/Al2O3, KF (base), and O2 (terminal oxidant), various structurally diverse N-acylsulfenamides could be synthesized through aerobic cross-dehydrogenative coupling of benzenethiols and cyclic amides.
