39875-70-2Relevant academic research and scientific papers
Crystal-packing modes determine the solid-state ESIPT fluorescence in highly dipolar 2′-hydroxychalcones
Bordy, Mathieu,Bretonnière, Yann,Hasserodt, Jens,Jeanneau, Erwann,Tordo, Alix
supporting information, p. 12727 - 12731 (2021/10/06)
This work describes the systematic study of the structure-luminescence relationship of 15 hydroxy-chalcones directly in the crystal state. Chalcones are easily assembled at the gram scale allowing for efficient variation of their substitution motifs. Our molecule variants combine two modes of fluorescence generation, ESIPT and ICT, both known for their potential to achieve significant quantum yields even with emission in the red to near infrared, a region preferred for technologies as diverse as optoelectronics and chemical sensing. Quantum yields as high as 48% (at 665 nm) and emission wavelengths in the deep red region (710 nm, 5%) were achieved with variants equipped with a strained amino substituent in the donor portion (azetidinyl). Systematic XRD analysis of large monocrystals allowed for the identification of the subtle interplay of several inter- and intra-molecular parameters in achieving such performances, be it intramolecular planarity, non-classical H-bonds, and stacking modes.
Synthesis of novel fluorescent parent nucleus containing chalcone structure
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Paragraph 0014-0017, (2020/05/02)
The invention discloses a fluorescent parent nucleus containing a chalcone structure. The fluorescent parent nucleus has the following general formula shown in the specification. The invention discloses a synthesis method of a novel fluorescent parent nuc
POLYPHENOL ANALOGS TO TREAT ISCHEMIA
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Page/Page column 82, (2013/03/26)
The present invention provides methods of use of polyphenol compounds for treating, preventing, mitigating and delaying ischemia or a condition where ischemia occurs. In one embodiment, the method comprises providing a polyphenol analog; and administering
NEUROPROTECTIVE POLYPHENOL ANALOGS
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Page/Page column 82, (2013/03/26)
The present invention provides neuroprotective polyphenol compounds, which can be synthetic analogs of fisetin, baicalein or chlorogenic acid, that maintain neuroprotective, anti-inflammatory, glutathione promoting, and/or antioxidant properties. The neur
Chemical modification of the multitarget neuroprotective compound fisetin
Chiruta, Chandramouli,Schubert, David,Dargusch, Richard,Maher, Pamela
supporting information; experimental part, p. 378 - 389 (2012/03/10)
Many factors are implicated in age-related central nervous system (CNS) disorders, making it unlikely that modulating only a single factor will provide effective treatment. Perhaps a better approach is to identify small molecules that have multiple biolog
