39891-85-5Relevant academic research and scientific papers
Acidic Isomerization of Vicinally Substituted (cis)-Acceptor-Donor Cyclopropanes via an Open Ring Mechanism
Dechoux, Luc,Doris, Eric
, p. 2017 - 2020 (1994)
Many (cis)-cyclopropanes bearing 1-electronwithdrawing and 2-hydroxymethylene groups were synthesized under mild acidic conditions to afford the corresponding trans isomers.The mechanism is reported.
Cyclopropane-containing polyamine analogues are efficient growth inhibitors of a human prostate tumor xenograft in nude mice
Frydman, Benjamin,Blokhin, Andrei V.,Brummel, Sara,Wilding, George,Maxuitenko, Yulia,Sarkar, Aparajita,Bhattacharya, Subhra,Church, Dawn,Reddy, Venodhar K.,Kink, John A.,Marton, Laurence J.,Valasinas, Aldonia,Basu, Hirak S.
, p. 4586 - 4600 (2007/10/03)
Polyamine analogues 7, 10, 18, 27, and 32 containing cyclopropane rings were obtained by chemical synthesis. Their antineoplastic activities were assessed against the cultured human prostate tumor cell lines DU-145, DuPro, and PC-3. Decamines 32 and 27 ex
