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1-(4-fluorophenyl)ethyl chloroformate is an organic compound with the chemical formula C9H8ClFO2. It is a colorless liquid that is soluble in organic solvents. 1-(4-fluorophenyl)ethyl chloroformate is a derivative of chloroformic acid ester, where the hydroxyl group of chloroformic acid is replaced by a 1-(4-fluorophenyl)ethyl group. It is synthesized by reacting 4-fluorophenylethylamine with chloroformic acid in the presence of a base. 1-(4-fluorophenyl)ethyl chloroformate is used as a reagent in organic synthesis, particularly in the preparation of various pharmaceuticals and agrochemicals. It is also known for its potential applications in the synthesis of biologically active compounds due to its unique structure and reactivity.

399-02-0

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399-02-0 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 399-02-0 includes 6 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 3 digits, 3,9 and 9 respectively; the second part has 2 digits, 0 and 2 respectively.
Calculate Digit Verification of CAS Registry Number 399-02:
(5*3)+(4*9)+(3*9)+(2*0)+(1*2)=80
80 % 10 = 0
So 399-02-0 is a valid CAS Registry Number.

399-02-0Downstream Products

399-02-0Relevant academic research and scientific papers

Deoxygenative cross-electrophile coupling of benzyl chloroformates with aryl iodides

Pan, Yingying,Gong, Yuxin,Song, Yanhong,Tong, Weiqi,Gong, Hegui

, p. 4230 - 4233 (2019)

This work describes Ni-catalyzed cross-electrophile coupling of benzyl chloroformate derivatives with aryl iodides that generates a wide range of diaryl methane products. The mild reaction conditions merit the C-O bond radical fragmentation of benzyl chloroformates via halide abstraction or a single electron reduction by a Ni catalyst. This work offers a new substrate type for cross-electrophile couplings.

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