399-40-6

Basic information

• Product Name: (2-BROMO-4-FLUORO-PHENOXY)-ACETIC ACID
• Synonyms: Aceticacid, (2-bromo-4-fluorophenoxy)- (6CI,8CI,9CI); (2-Bromo-4-fluorophenoxy)aceticacid; NSC 190612
• CAS NO: 399-40-6
• Molecular Formula: C₈H₆BrFO₃
• Molecular Weight: 0
• Mol File: 399-40-6.mol
• Article Data: 2

Chemical Properties

• Boiling Point: 341.8°Cat760mmHg
• Flash Point: 160.5°C
• Appearance: /
• Density: 1.717g/cm³
• Vapor Pressure: 3.02E-05mmHg at 25°C
• Refractive Index: 1.559
• CAS DataBase Reference: (2-BROMO-4-FLUORO-PHENOXY)-ACETIC ACID(CAS DataBase Reference)
• NIST Chemistry Reference: (2-BROMO-4-FLUORO-PHENOXY)-ACETIC ACID(399-40-6)
• EPA Substance Registry System: (2-BROMO-4-FLUORO-PHENOXY)-ACETIC ACID(399-40-6)

Safety Data

• Hazardous Substances Data: 399-40-6(Hazardous Substances Data)

Usage

General Description

(2-Bromo-4-fluoro-phenoxy)-acetic acid, also known as 2-Bromo-4-fluorophenoxyacetic acid, is a chemical compound with the molecular formula C8H6BrFO3. It is a derivative of acetic acid and contains a phenyl ring with a bromine and fluorine atom attached. (2-BROMO-4-FLUORO-PHENOXY)-ACETIC ACID is commonly used in the synthesis of pharmaceuticals and agricultural chemicals. It has also been studied for its potential as an herbicide. "(2-Bromo-4-fluoro-phenoxy)-acetic acid" has a variety of applications in the fields of medicine, agriculture, and chemical research.

InChI:InChI=1/C8H6BrFO3/c9-6-3-5(10)1-2-7(6)13-4-8(11)12/h1-3H,4H2,(H,11,12)

Upstream product

• 405-79-8 2-(4-fluorophenoxy)ethanoic acid 
• 371-41-5 4-Fluorophenol 
• 904297-82-1 tert-butyl (2-bromo-4-fluorophenoxy)acetate 
• 371-40-4 4-fluoroaniline 
• 496-69-5 2-bromo-4-fluoro-phenol 
• 79-11-8 chloroacetic acid 

Downstream Products

• 904297-93-4 tetrahydro-thiopyran-4-carboxylic acid N'-[2-(2-bromo-4-fluoro-phenoxy)-acetyl]-N'-isopropyl-hydrazide 
• 904297-90-1 4-(2-methoxy-ethoxy)-benzoic acid N'-[2-(2-bromo-4-fluoro-phenoxy)-acetyl]-N'-isopropyl-hydrazide 
• 904297-89-8 cyclohexanecarboxylic acid N'-[2-(2-bromo-4-fluoro-phenoxy)-acetyl]-N'-isopropyl-hydrazide 

Relevant articles and documents

Design and Synthesis of Novel 4-Hydroxyl-3-(2-phenoxyacetyl)-pyran-2-one Derivatives for Use as Herbicides and Evaluation of Their Mode of Action

In order to develop a novel herbicide containing the β-triketone motif, a series of 4-hydroxyl-3-(2-phenoxyacetyl)-pyran-2-one derivatives were designed and synthesized. The bioassay results showed that compound II15 had good pre-emergent herbicidal activity even at a dosage of 187.5 g ha-1. Moreover, compound II15 showed a broader spectrum of weed control when compared with a commercial herbicide 2,4-dichlorophenoxyacetic acid (2,4-D), and displayed good crop safety to Triticum aestivum L. and Zea mays Linn. when applied at 375 g ha-1 under pre-emergence conditions, which indicated its great potential as a herbicide. More importantly, studying the molecular mode of action of compound II15 revealed that the novel triketone structure is a proherbicide of its corresponding phenoxyacetic acid auxin herbicide, which has a herbicidal mechanism similar to that of 2,4-D. The present work indicates that the 4-hydroxyl-3-(2-phenoxyacetyl)-pyran-2-one motif may be a potential lead structure for further development of novel auxin-type herbicides.