399-53-1 Usage
Uses
Used in Polymer Synthesis:
2,4-Difluoro-1-vinyl-benzene is used as a monomer in the polymer industry for its ability to improve the thermodynamic stability and chemical resistance of the resulting polymers. The presence of fluorine atoms and the vinyl group in the compound contributes to the enhanced properties of the polymers, making them suitable for various applications.
Used in Chemical Industry:
In the chemical industry, 2,4-difluoro-1-vinyl-benzene is used as an intermediate in the synthesis of various compounds and materials. Its reactivity with other substances allows for the creation of new chemical entities with specific properties, making it a versatile component in chemical processes.
Used in Fluoropolymer Production:
2,4-Difluoro-1-vinyl-benzene is used as a key component in the production of fluoropolymers, which are known for their exceptional thermal stability, chemical resistance, and non-stick properties. These fluoropolymers find applications in various industries, including automotive, aerospace, electronics, and medical fields.
Used in Coatings and Adhesives:
The enhanced chemical resistance and stability of 2,4-difluoro-1-vinyl-benzene make it suitable for use in the development of high-performance coatings and adhesives. These coatings and adhesives can withstand harsh environmental conditions and provide excellent adhesion to various surfaces, making them ideal for use in industrial applications.
Used in Pharmaceutical and Agrochemical Industries:
2,4-Difluoro-1-vinyl-benzene can also be used as a building block in the synthesis of pharmaceuticals and agrochemicals. Its unique structure and reactivity allow for the development of new compounds with specific therapeutic or pesticidal properties, contributing to advancements in these industries.
Check Digit Verification of cas no
The CAS Registry Mumber 399-53-1 includes 6 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 3 digits, 3,9 and 9 respectively; the second part has 2 digits, 5 and 3 respectively.
Calculate Digit Verification of CAS Registry Number 399-53:
(5*3)+(4*9)+(3*9)+(2*5)+(1*3)=91
91 % 10 = 1
So 399-53-1 is a valid CAS Registry Number.
InChI:InChI=1/C8H6F2/c1-2-6-3-4-7(9)5-8(6)10/h2-5H,1H2
399-53-1Relevant academic research and scientific papers
QUINAZOLINONE DERIVATIVES AS VIRAL POLYMERASE INHIBITORS
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Page/Page column 83, (2011/04/19)
Compounds of formula I: (I) wherein X, R2, R3, R5 and R6 are defined herein, are useful as inhibitors of the hepatitis C virus NS5B polymerase.
Selective 5-hydroxytryptamine 2c receptor agonists derived from the lead compound tranylcypromine: Identification of drugs with antidepressant-like action
Sung, Jin Cho,Jensen, Niels H.,Kurome, Toru,Kadari, Sudhakar,Manzano, Michael L.,Malberg, Jessica E.,Caldarone, Barbara,Roth, Bryan L.,Kozikowski, Alan P.
experimental part, p. 1885 - 1902 (2009/12/07)
We report here the design, synthesis, and pharmacological properties of a series of compounds related to tranylcypromine (9), which itself was discovered as a lead compound in a high-throughput screening campaign. Starting from 9, which shows modest activity as a 5-HT2C agonist, a series of 1-aminomethyl-2- phenylcyclopropanes was investigated as 5-HT2C agonists through iterative structural modifications. Key pharmacophore feature of this new class of ligands is a 2-aminomethyl-trans-cyclopropyl side chain attached to a substituted be zene ring. Among the tested compounds, several were potent and efficacious 5-HT2C receptor agonists with selectivity over both 5-HT2A and 5-HT2B receptors in functional assays. The most promising compound is 37, with 120- and 14-fold selectivity over 5-HT 2A and 5-HT2B, respectively (EC50) 585, 65, and 4.8 nM at the 2A, 2B, and 2C subtypes, respectively). In animal studies, compound 37 (10-60 mg/kg) decreased immobility time in the mouse forced swim test.
