399040-13-2

Basic information

• Product Name: 3-Furancarbonitrile, 2-amino-4-(4-chlorophenyl)-
• CAS NO: 399040-13-2
• Molecular Formula: C11H7ClN2O
• Molecular Weight: 218.642
• Mol File: 399040-13-2.mol
• Article Data: 4

Chemical Properties

• CAS DataBase Reference: 3-Furancarbonitrile, 2-amino-4-(4-chlorophenyl)-(CAS DataBase Reference)
• NIST Chemistry Reference: 3-Furancarbonitrile, 2-amino-4-(4-chlorophenyl)-(399040-13-2)
• EPA Substance Registry System: 3-Furancarbonitrile, 2-amino-4-(4-chlorophenyl)-(399040-13-2)

Safety Data

• Hazardous Substances Data: 399040-13-2(Hazardous Substances Data)

Upstream product

• 27993-56-2 1-(4-chlorophenyl)-2-hydroxyethanone 
• 109-77-3 malononitrile 
• 104-88-1 4-chlorobenzaldehyde 

Downstream Products

• 141764-46-7 5-(4-chlorophenyl)furo[2,3-d]pyrimidin-4(3H)-one 

Relevant articles and documents

COMPOUNDS USEFUL IN HIV THERAPY

The invention relates to compounds of Formulas (I), (II) and (III) salts thereof, pharmaceutical compositions thereof, as well as methods of treating, curing or preventing HIV in subjects.

FURANOPYRIMIDINE COMPOUNDS EFFECTIVE AS POTASSIUM CHANNEL INHIBITORS

A compound of formula (I) wherein R1 is aryl, heteroaryl, cycloalkyl or alkyl; R2 is H, alkyl, nitro, -CO2R7, CONR4R5 or halo; R3 is H, NR4R5, NC(O)R8, halo, trifluoromethyl, alkyl, nitrile or alkoxy; R4 and R5 may be the same or different, and may be H, alkyl, aryl, heteroaryl or cycloalkyl; or R4 and R5 may together form a saturated, unsaturated or partially saturated 4 to 7 member ring, wherein said ring may optionally comprise one or more further heteroatoms selected from N, O or S; X is O, S or NR6; R6 is H or alkyl; R7 is hydrogen, methyl or ethyl; R8 is methyl or ethyl; Ll is (CH2)n, where n is 1,2 or 3; and Y is aryl, a heterocyclic group, alkyl, alkenyl or cycloalkyl; together with pharmaceutically acceptable salts thereof. The use of these compounds as potassium channel inhibitors is also described.