3991-53-5

Upstream product

• 68-26-8 RETINOL 
• 603-35-0 triphenylphosphine 
• 127-47-9 Retinol acetate 

Downstream Products

• 1107-26-2 trans-β-apo-8'-carotenal 
• 1109-11-1 trans-apo-8'-carotenic acid ethyl ester 
• 85098-47-1 1,12-Bis(2,6,6-trimethylcyclohex-1-enyl)-3,7-dimethyldodeca-1,3,5,7,9,11-hexaene 
• 5056-11-1 Torularhodin-ethylester 
• 5999-29-1 all-E-3',4'-didehydro-β,ψ-caroten-16'-al 
• 105765-75-1 all-E-3',4'-didehydro-2'-apo-β,ψ-caroten-2'-al 
• 7235-40-7 beta-carotene 

Relevant academic research and scientific papers

Preparation method of β - carotene with high total trans content

The invention provides a preparation method of β - carotene with a high total trans content. Starting from the vitamin A derivative, C20 phosphine salt is obtained through reaction with triphenylphosphine, and the C20 phosphine salt is subjected to condensation reaction under the action IBX high iodine compound and base to obtain β - carotene containing cis-trans, and then the β - carotene with high trans content is obtained under the action of a transition metal loading catalyst. The method avoids the use of a strong oxidizing agent in the traditional process, is environmentally friendly and can reduce the peroxidation of β - carotene, so that the reaction yield is increased, and the transition metal catalyst enables the obtained β - carotene content to be full. Trans increase.

Isolation and Identification of the Polyenes Formed During the Thermal Degradation of β,β-Carotene

It has been proposed that carotenoid natural products are the source of part of the aromatic fraction of petroleum.In order to understand the mechanisms by which carotenoids are converted to aromatic products, an investigation of the polyene intermediates formed in the thermal degradation of β,β-carotene was initiated.As a result of this investigation, four polyene intermediates have been isolated and identified: 1,12-bis(2,6,6-trimethylcyclohex-1-enyl)-3,6,10-trimethyldodeca-1,3,5,7,9,11-hexaene, 1,12-bis(2,6,6-trimethylcyclohex-1-enyl)-3,7-dimethyldodeca-1,3,5,7,9, 11-hexaene, 1,6-bis(2,6,6-trimethylcyclohex-1-enyl)-3-methylhexa-1,3,5-triene, and 1,6-bis(2,6,6-trimethylcyclohex-1-enyl)hexa-1,3,5-triene.Independent syntheses confirmed the structures of the polyene intermediates. 1H NMR established the type and number of methyl substituents.Mass spectra of the saturated analogues confirmed the positions of the in-chain methyl substituents.The structures of the polyene intermediates are consistent with proposals that β,β-carotene thermally degrades by a series of symmetry-allowed electrocyclic processes followed by a thermal elimination.However, not all of the degradation products arise from electrocyclic-type processes.The presence of 1,1,3-trimethylcyclohexane and long chain aromatics indicates that disproportionation reactions are occurring in the complex degradation reaction.