399513-53-2Relevant academic research and scientific papers
Chemoselective cross metathesis of bishomoallylic alcohols: Rapid access to fragment A of the cryptophycins
Lautens, Mark,Maddess, Matthew L.
, p. 1883 - 1886 (2007/10/03)
Equation presented. The racemic or enantioselective allylation of in situ formed β,γ-unsaturated aldehydes provides efficient access to bishomoallylic alcohols from readily available 2-vinyloxiranes. These products, when subjected to modified Grubbs cross
Enantioselective allylation of β,γ-unsaturated aldehydes generated via Lewis acid induced rearrangement of 2-vinyloxiranes
Lautens, Mark,Maddess, Matthew L.,Sauer, Effiette L. O.,Ouellet, Stephane G.
, p. 83 - 86 (2007/10/03)
(matrix presented) 2-Vinyloxiranes have been found to be excellent surrogates to β,γ-unsaturated aldehydes. These valuable electrophiles, generated in situ by treatment of a 2-vinyloxirane with a catalytic amount of Sc(OTf)3, are effectively tr
