39959-68-7 Usage
Uses
Used in Pharmaceutical Chemistry:
1-[2-(Trifluoromethyl)phenyl]ethylamine Hydrochloride is used as a chemical intermediate for the synthesis of various pharmaceutical compounds. The presence of the trifluoromethyl group in its structure contributes to its potential biological activity, which is valuable in the development of new drugs.
Used in Scientific Research and Development:
1-[2-(Trifluoromethyl)phenyl]ethylamine Hydrochloride is used as a research compound in laboratories, where it aids in the exploration of new chemical reactions and the synthesis of novel compounds. Its unique structure and properties make it a valuable tool for scientific investigations.
Used in Fluoro-compounds and Phenyl-amino-compounds Synthesis:
1-[2-(Trifluoromethyl)phenyl]ethylamine Hydrochloride is used as a key building block in the synthesis of fluoro-compounds and phenyl-amino-compounds. Its structure provides a foundation for the creation of new molecules with potential applications in various fields, including medicine and materials science.
Check Digit Verification of cas no
The CAS Registry Mumber 39959-68-7 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 3,9,9,5 and 9 respectively; the second part has 2 digits, 6 and 8 respectively.
Calculate Digit Verification of CAS Registry Number 39959-68:
(7*3)+(6*9)+(5*9)+(4*5)+(3*9)+(2*6)+(1*8)=187
187 % 10 = 7
So 39959-68-7 is a valid CAS Registry Number.
InChI:InChI=1/C9H10F3N.ClH/c1-6(13)7-4-2-3-5-8(7)9(10,11)12;/h2-6H,13H2,1H3;1H
39959-68-7Relevant academic research and scientific papers
Sequential reductive amination-hydrogenolysis: A one-pot synthesis of challenging chiral primary amines
Nugent, Thomas C.,Negru, Daniela E.,El-Shazly, Mohamed,Hu, Dan,Sadiq, Abdul,Bibi, Ahtaram,Umar, M. Naveed
supporting information; experimental part, p. 2085 - 2092 (2011/10/19)
Difficult-to-access chiral primary amines were formed in good to high yield and ee using a rare example of a one-pot synthesis from prochiral ketones (sequential reductive amination-hydrogenloysis). As a highlight we also demonstrate a one-pot reductive amination-hydrogenolysis-reductive amination (five reactions) of ortho-methoxyacetophenone resulting in the chiral diamine 1-(2-methoxyphenyl)ethyl-(2-pyridylmethyl)-amine (4) (58% overall yield, >99% ee), a new organocatalyst for aqueous enantioselective aldol reactions. Copyright
