3996-28-9 Usage
Uses
Used in Organic Synthesis:
4-[(E)-(3-nitrophenyl)methylidene]aminobenzoic acid is used as an intermediate in organic synthesis for the creation of various complex organic molecules. Its unique structure allows for versatile reactions and the formation of a wide range of chemical products.
Used in Pharmaceutical Research:
In the pharmaceutical industry, 4-[(E)-(3-nitrophenyl)methylidene]aminobenzoic acid is used as a key component in drug discovery and development. Its potential applications in the creation of new drugs are being explored due to its distinctive chemical properties, which may contribute to the development of innovative therapeutic agents.
Used in Drug Development:
4-[(E)-(3-nitrophenyl)methylidene]aminobenzoic acid is employed as a building block in the design and synthesis of new pharmaceutical compounds. Its unique structure and reactivity make it a valuable asset in the development of novel drugs with potential therapeutic benefits.
Safety Considerations:
It is important to handle 4-[(E)-(3-nitrophenyl)methylidene]aminobenzoic acid with care, as it may have toxic or harmful effects if not used properly. Adequate safety measures should be taken during its synthesis, storage, and application to minimize any potential risks associated with its use.
Check Digit Verification of cas no
The CAS Registry Mumber 3996-28-9 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 3,9,9 and 6 respectively; the second part has 2 digits, 2 and 8 respectively.
Calculate Digit Verification of CAS Registry Number 3996-28:
(6*3)+(5*9)+(4*9)+(3*6)+(2*2)+(1*8)=129
129 % 10 = 9
So 3996-28-9 is a valid CAS Registry Number.
3996-28-9Relevant academic research and scientific papers
Synthesis of novel β-amino ketones containing a p-aminobenzoic acid moiety and evaluation of their antidiabetic activities
Tang, Guangxia,Yan, Jufang,Fan, Li,Xu, Jin,Song, Xiaoli,Jiang, Li,Luo, Lingfei,Yang, Dacheng
, p. 490 - 504 (2013/07/11)
The synthesis of two series of β-amino ketones containing a p-aminobenzoic acid moiety (TM-1 and TM-2) using a modified protocol of the Mannich reaction is reported. The molecular structures of a total of tweenty three new target compounds were characterized by 1H NMR, 13C NMR, ESI-MS and HR-MS. Subsequently, their antidiabetic activities were screened in vitro. The α-glucodase inhibition (α-GI) activity of compound 1e reached a remarkable level of 66.50%. The peroxisome proliferator-activated receptor (PPAR) relative activation activities of six compounds are above 80%, and in particular 2i displays an unprecedentedly high PPAR of 130.91%. The structure-activity relationships of the compounds were established. 2i is also subject to further in-depth investigation.
Spectroscopic, structural and solution studies of new Tl(I) complex with 3-nitrobenzylidene-4-aminobenzoic acid
Rahimi, Rahmatollah,Eskandari, Maryam
experimental part, p. 1929 - 1931 (2012/02/15)
A new thallium(I) complex with a Schiff base ligand, [Tl(L)](1) [L- = 3-nitrobenzylidene-4-aminobenzoic acid], has been synthesized and characterized. The carboxylic groups of the ligand 3-nitrobenzylidene-4-aminobenzoic acid in the new Tl(I) complex is c
