39978-69-3

Usage

Uses

Used in Medicinal Chemistry:
1-(1-adamantyl)propan-2-amine is used as a research compound for its structural and pharmacological similarities to other psychoactive substances, aiding in the development of new medications and understanding of the central nervous system.
Used in Drug Development:
APTA is utilized as a lead compound in the design and synthesis of novel psychoactive drugs, potentially offering new therapeutic options for various conditions.
Used in Neuropharmacological Research:
1-(1-adamantyl)propan-2-amine is employed as a research tool in neuropharmacology to study the effects of psychoactive substances on the central nervous system and to explore their mechanisms of action.
Used in Regulatory and Forensic Analysis:
Due to its potential for misuse and abuse, 1-(1-adamantyl)propan-2-amine is used in regulatory and forensic analysis to monitor and control its distribution and consumption, ensuring public safety and compliance with legal standards.

InChI:InChI=1/C19H27N/c1-13(20)6-17-4-2-3-5-18(17)19-10-14-7-15(11-19)9-16(8-14)12-19/h2-5,13-16H,6-12,20H2,1H3

Upstream product

• 78679-77-3 1-Adamantyl-2-propanone oxime 
• 19835-39-3 1-(1-adamantyl)propan-2-one 

Downstream Products

• 56558-39-5 (2-Adamantan-1-yl-1-methyl-ethyl)-[1-(4-chloro-phenyl)-meth-(E)-ylidene]-amine 
• 56558-38-4 (2-Adamantan-1-yl-1-methyl-ethyl)-[1-(4-methoxy-phenyl)-meth-(E)-ylidene]-amine 
• 1192412-58-0 2-{[1-(1-adamantyl)prop-2-yl]amino}-6-benzyl-5-methylpyrimidin-4(3H)-one 
• 1283234-27-4 C₁₉H₂₇N 
• 1283234-64-9 N,N'-bis[2-(1-adamantyl)-1-methylethyl]benzene-1,2-diamine 
• 1283234-61-6 N-[2-(1-adamantyl)-1-methylethyl]-2-bromoaniline 
• 1283234-62-7 N,N'-bis[2-(1-adamantyl)-1-methylethyl]benzene-1,4-diamine 
• 1283234-59-2 N-[2-(1-adamantyl)-1-methylethyl]-4-bromoaniline 
• 1283234-63-8 N,N'-bis[2-(1-adamantyl)-1-methylethyl]benzene-1,3-diamine 
• 1283234-60-5 N-[2-(1-adamantyl)-1-methylethyl]-3-bromoaniline 
• 1283234-58-1 N-[2-(1-adamantyl)-1-methylethyl]-2-chloroaniline 
• 1283234-57-0 N-[2-(1-adamantyl)-1-methylethyl]-3-chloroaniline 
• 1283234-56-9 N-[2-(1-adamantyl)-1-methylethyl]-4-chloroaniline 
• 1283234-31-0 N¹-[α-(1-adamantyl)benzyl]-N³-[2-(1-adamantyl)-1-methylethyl]benzene-1,3-diamine 

Relevant academic research and scientific papers

Synthesis of a new family of adamantylpyridin-2-amines by palladium-catalyzed amination

Palladium-catalyzed arylation of various adamantane-containing amines with 2-bromopyridine has been studied, and the influence of the phosphane ligand, concentration, and molar ratio of the reagents on the composition of the reaction mixture and on the yield of the target adamantylpyridin-2-amines has been analyzed. The dependence of the formation of N,N-diarylated products on the nature of the starting adamantylamines is shown. Georg Thieme Verlag Stuttgart.

Anorectic adamantane derivatives and method of using the same

Adamantane derivatives such as β-(1-adamantyl)-α,α-dimethylethylamine hydrochloride, β-(1-adamantyl)-α-methylethylamine hydrochloride, d-β-(1-adamantyl)-α-methylethylamine hydrochloride, and 1-β-(1-adamantyl)-α-methylethylamine hydrochloride have anorectic activity. The hydrazine derivatives of the above compounds are antihypertensive agents, and monoamine oxidase inhibitors.