39979-08-3

Usage

Uses

Used in Pharmaceutical Production:
7-Aminoheptanoic acid methyl ester is used as a building block in the synthesis of various drugs for its ability to be incorporated into complex molecular structures, contributing to the development of new therapeutic agents.
Used in Organic Synthesis:
As a chemical intermediate, 7-Aminoheptanoic acid methyl ester is used in organic synthesis to facilitate the creation of a wide range of chemical compounds, expanding its utility across different chemical applications.
Used in Biochemical Buffer Formulation:
7-Aminoheptanoic acid methyl ester is used as a component in the formulation of biochemical buffers, helping to maintain stable pH conditions in various biological and chemical processes.
Used in Research and Development:
7-Aminoheptanoic acid methyl ester is studied for its potential pharmacological properties, such as anti-fibrinolytic and antihyperlipidemic effects, making it a candidate for further research and development in the pharmaceutical industry. This research aims to explore its therapeutic potential and possible applications in treating various medical conditions.

Upstream product

• 502-44-3 hexahydro-2H-oxepin-2-one 
• 67-56-1 methanol 
• 143-33-9 sodium cyanide 
• 929-17-9 7-aminoheptanoic acid 
• 13154-41-1 methyl 7-nitroheptanoate 
• 60142-89-4 7-[(tert-butoxycarbonyl)amino]heptanoic acid 
• 111-26-2 hexan-1-amine 
• 201230-82-2 carbon monoxide 

Relevant academic research and scientific papers

Studying Histone Deacetylase Inhibition and Apoptosis Induction of Psammaplin A Monomers with Modified Thiol Group

Psammaplin A (PsA) is a bromotyrosine disulfide dimer with histone deacetylase (HDAC) inhibition and acts through reduced monomer PsA-SH. We studied the connection of HDAC inhibition, cell growth inhibition, and apoptosis induction of PsA-SH by modifying the -SH group with deletion (6a) or replacement with hydroxamic acid (10b) or benzamide (12g). PsA-SH inhibits HDAC1/2/3 and 6a loses the HDAC inhibition ability. 10b inhibits HDAC1/2/3/6 while 12g shows selective inhibition of HDAC3. PsA-SH and 10b, but neither 6a nor 12g, induce apoptosis in human leukemia HL-60 cells associated with increased acetylation of Histone H3. PsA-SH and 10b inhibit growth of several solid tumor cell lines in vitro and Lewis lung cancer cell growth in vivo. PsA-SH is a simple scaffold for developing selective HDAC inhibitors and induces apoptosis through inhibiting HDAC1/2.

IDENTIFICATION OF KINASE INHIBITORS

The invention concerns the identification of protein kinase inhibitors that preferentially bind to the inactive conformation of a target protein kinase. The inhibitors are identified by locking the target protein kinase in an inactive conformation, and us

Electro-organic synthesis of N-hexyl carbamate by carbonylation of methanol and hexylamine with CO over Au supported on carbon anode

It has been found that Au anode, [AuBr3/AC+VGCF], showed the electro-catalysis for carbonylation of methanol, hexylamine and CO to 6-amino-hexyl-carbamic acid methyl ester (N-hexyl carbamate) using LiBr electrolyte.

Reduction of Aliphatic and Aromatic Nitro Compounds with Sodium Borohydride in Tetrahydrofuran Using 10percent Palladium-on-Carbon as Catalyst

Aliphatic and aromatic nitro compounds are reduced to amino compounds in good yields with sodium borohydride in tetrahydrofuran using 10percent palladium-on-carbon as catalyst.