400-01-1

Basic information

• Product Name: 2,4,5-TriMethylfluorobenzene
• Synonyms: 2,4,5-TriMethylfluorobenzene
• CAS NO: 400-01-1
• Molecular Formula: C₉H₁₁F
• Molecular Weight: 138.1820432
• Mol File: 400-01-1.mol

Chemical Properties

• Boiling Point: 175.4±9.0 °C(Predicted)
• Appearance: /
• Density: 0.969±0.06 g/cm3(Predicted)
• CAS DataBase Reference: 2,4,5-TriMethylfluorobenzene(CAS DataBase Reference)
• NIST Chemistry Reference: 2,4,5-TriMethylfluorobenzene(400-01-1)
• EPA Substance Registry System: 2,4,5-TriMethylfluorobenzene(400-01-1)

Safety Data

• Hazardous Substances Data: 400-01-1(Hazardous Substances Data)

Usage

Uses

Used in Chemical Industry:
2,4,5-Trimethylfluorobenzene is utilized as a solvent in various chemical processes, providing a medium for reactions to occur. Its properties make it suitable for dissolving a wide range of substances, facilitating the synthesis of new compounds and the manufacturing of various products.
Used in Pharmaceutical Industry:
In the pharmaceutical sector, 2,4,5-Trimethylfluorobenzene is employed as a solvent for the synthesis of active pharmaceutical ingredients. Its ability to dissolve a variety of compounds aids in the development of new drugs and the improvement of existing formulations.
Used in Research and Development:
2,4,5-Trimethylfluorobenzene is also used as a research tool in laboratories, where it serves as a solvent for conducting experiments and testing new chemical reactions. Its versatility in dissolving different substances makes it valuable for scientific exploration and innovation.
Used in Specialty Chemicals Production:
2,4,5-Trimethylfluorobenzene is employed in the production of specialty chemicals, such as fragrances, dyes, and other organic compounds. Its solvent properties enable the efficient synthesis of these chemicals, contributing to the creation of unique and high-quality products.

Upstream product

• 137-17-7 2,4,5-trimethylaniline 
• 95-63-6 1,2,4-Trimethylbenzene 
• 95-93-2 1,2,4,5-tetramethylbenzene 

Relevant articles and documents

Metal-Catalyzed Carbon-Fluorine Bond Formation

One aspect of the invention relates to a metal-catalyzed conversion of aryl halides and sulfonates to the corresponding aryl fluorides. Another aspect of the invention relates to a metal-catalyzed conversion of heteroaryl halides and sulfonates to the corresponding heteroaryl fluorides. Another aspect of the invention relates to a metal-catalyzed conversion of vinyl halides and sulfonates to the corresponding vinyl fluorides. In certain embodiments, simple fluoride sources, such as AgF and CsF, are used. In certain embodiments, the transformations tolerate a wide range of functional groups, allowing for introduction of fluorine atoms into highly functionalized organic molecules.

Effect of Catalyst on the Fluorination of Methyl-Substituted Benzenes with Xenon Difluoride

The course of acid-catalyzed liquid-phase fluorination of methyl-substituted benzene derivatives with xenon difluoride depends strongly on the structure and concentration of the substrate, its molar ratio to xenon difuoride, and the catalyst.HF-catalyzed