400-23-7 Usage
General Description
2-Nitro-4-(trifluoromethylsulfonyl)aniline is a chemical compound that belongs to the class of anilines, which are organic compounds with a phenyl group attached to an amino group. This particular compound is characterized by the presence of a nitro group (NO2) and a trifluoromethylsulfonyl group (CF3SO2), both of which are highly reactive and can have various applications in organic synthesis and pharmaceuticals. The nitro group can undergo reduction reactions to produce amino groups, while the trifluoromethylsulfonyl group is commonly used as a leaving group in organic chemistry reactions. 2-NITRO-4-(TRIFLUOROMETHYLSULFONYL)ANILINE may also have potential uses in the development of agrochemicals, pharmaceuticals, and materials science due to its unique chemical properties. However, it is important to handle this compound with care, as it may pose health and environmental risks due to its reactivity and toxicity.
Check Digit Verification of cas no
The CAS Registry Mumber 400-23-7 includes 6 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 3 digits, 4,0 and 0 respectively; the second part has 2 digits, 2 and 3 respectively.
Calculate Digit Verification of CAS Registry Number 400-23:
(5*4)+(4*0)+(3*0)+(2*2)+(1*3)=27
27 % 10 = 7
So 400-23-7 is a valid CAS Registry Number.
InChI:InChI=1/C7H5F3N2O4S/c8-7(9,10)17(15,16)4-1-2-5(11)6(3-4)12(13)14/h1-3H,11H2
400-23-7Relevant articles and documents
Synthesis and in vitro antibacterial activity of 5-halogenomethylsulfonyl- benzimidazole and benzotriazole derivatives
Ochal, Zbigniew,Bretner, Maria,Wolinowska, Renata,Tyski, Stefan
, p. 1129 - 1136 (2014/01/06)
A series of 5-halogenomethylsulfonylbenzimidazole and benzotriazole derivatives was synthesized as potential antibacterial agents. A new method of synthesis of benzimidazoles was developed. The antimicrobial activities of these compounds were tested against a series of reference and clinical strains. The reference strains include Gram-positive bacteria (S. aureus, S. epidermidis, B. subtilis, B. cereus, E. hirae, M. luteus) and Gram-negative rods (E. coli, P. vulgaris, P. aeruginosa, B. bronchiseptica). The clinical strains include six methicillin-resistant (MRSA) and two methicillin-sensitive (MSSA) S. aureus strains, one methicillin-resistant S. epidermidis, three E. faecalis and two E. faecium strains. Compound with trifluoromethyl- substituent at C-2 position (4) displayed significant antibacterial activities comparable with nitrofurantoin against four strains, and higher against Micrococcus luteus. MIC values for clinical Staphylococci strains (MRSA) were 12.5-25 μg/mL; for Enterococcus strains these values were 50-100 μg/mL. MIC values for reference and clinical strains of Staphylococcus and Enterococcus group were similar, respectively.
