383-11-9

Basic information

• Product Name: 4-(TRIFLUOROMETHYLSULFONYL)CHLOBENZENE
• Synonyms: 4-(trifluoromethylsulfonyl)-1-chlorobenzene;4-(TRIFLUOROMETHYLSULPHONYL)CHLOROBENZENE;4-(TRIFLUOROMETHYLSULFONYL)CHLOBENZENE;4-TRIFLUOROMETHYLSULFONYL-CHLOROBENZENE;AURORA 23235;OTAVA-BB BB7211280016;4-[(Trifluoromethyl)sulphonyl]chlorobenzene, 1-Chloro-4-[(trifluoromethyl)sulphonyl]benzene;4-Chlorophenyl trifluoromethyl sulphone
• CAS NO: 383-11-9
• Molecular Formula: C₇H₄ClF₃O₂S
• Molecular Weight: 244.62
• Mol File: 383-11-9.mol
• Article Data: 12

Chemical Properties

• Melting Point: 61-61,5°C
• Appearance: /
• CAS DataBase Reference: 4-(TRIFLUOROMETHYLSULFONYL)CHLOBENZENE(CAS DataBase Reference)
• NIST Chemistry Reference: 4-(TRIFLUOROMETHYLSULFONYL)CHLOBENZENE(383-11-9)
• EPA Substance Registry System: 4-(TRIFLUOROMETHYLSULFONYL)CHLOBENZENE(383-11-9)

Safety Data

• Hazard Codes: Xi
• Statements: 20/21/22
• Safety Statements: 22-36/37/39
• Hazardous Substances Data: 383-11-9(Hazardous Substances Data)

Usage

General Description

4-(Trifluoromethylsulfonyl)chlorobenzene is a chemical compound with the molecular formula C7H4ClF3O2S. It is a white to off-white solid that is used as an intermediate in the manufacture of pharmaceuticals, agrochemicals, and other organic compounds. 4-(TRIFLUOROMETHYLSULFONYL)CHLOBENZENE is known for its strong and stable chemical structure, making it useful in a variety of applications. It is also used as a reagent in organic synthesis and as a building block for the production of other chemicals. 4-(Trifluoromethylsulfonyl)chlorobenzene is considered to be a hazardous substance, and appropriate safety precautions should be taken when handling and using it.

Upstream product

• 349-89-3 p-chlorobenzenesulfonyl fluoride 
• 754-25-6 trimethyl(trifluoromethyl)tin 
• 81290-20-2 (trifluoromethyl)trimethylsilane 
• 2314-97-8 iodotrifluoromethane 
• 100-03-8 4-chlorobenzenesulfinic acid 
• 358-23-6 trifluoromethylsulfonic anhydride 
• 108-90-7 chlorobenzene 
• 98-60-2 4-chlorobenzenesulfonyl chloride 
• 14752-66-0 sodium p-chlorobenzenesulphinate 
• 1961266-44-3 2,8-difluoro-5-(trifluoromethyl)-5H-dibenzo[b,d]thiophen-5-ium trifluoromethanesulfonate 
• 2926-29-6 Langlois reagent 
• 1204518-00-2 (4-chlorophenyl)(mesityl)iodonium trifluoromethanesulfonate 
• 75-46-7 trifluoromethan 
• 112425-78-2 S-(trifluoromethyl)diphenylsulfonium tetrafluoroborate 

Downstream Products

• 1550-27-2 1-chloro-2-nitro-4-[(trifluoromethyl)sulfonyl]benzene 
• 4837-29-0 p-trifluoromethylsulfonylphenylhydrazine 
• 19822-29-8 2,6-dinitro-4-((trifluoromethyl)sulfonyl)anisole 
• 83547-68-6 1-(2-hydroxyethoxy)-2,6-dinitro-4-((trifluoromethyl)sulfohyl)benzene 
• 264606-34-0 N-[4-(trifluoromethylsulfonyl)phenyl]-1,4-benzenediamine 
• 83642-43-7 4-(4-((trifluoromethyl)sulfonyl)phenoxy)-1,2-dichlorobenzene 
• 1204975-40-5 3-Benzyl-4,5-dimethyl-6-[(R)-3-methyl-4-(4-trifluoro-methanesulfonylphenyl)-piperazin-1-yl]-pyridazine 
• 76205-19-1 1-(para-chlorophenyl)-3-hydroxypyrazole 
• 17154-25-5 4-Trifluormethylsulfonyl-phenylsulfensaeure-triphenylphosphoranylidenamid 
• 50579-45-8 4-Butyloxy-3-nitro-benzolsulfonsaeure 
• 46403-72-9 4-methoxy-3-nitro-benzenesulfonic acid 
• 17162-44-6 Bis-(4-trifluormethylsulfonyl-phenylmercapto)-amin 
• 17162-49-1 4-Trifluormethylsulfonyl-phenylsulfensaeure-chlorid 
• 1869-28-9 (2-nitro-4-trifluoromethanesulfonyl-phenyl)-hydrazine 

Relevant articles and documents

Synthesis, Reactivity and Structural Properties of Trifluoromethylphosphoranides

Phosphoranides are interesting hypervalent species which serve as model compounds for intermediates or transition states in nucleophilic substitution reactions at trivalent phosphorus substrates. Herein, the syntheses and properties of stable trifluoromet

Practical and efficient synthesis of aryl trifluoromethyl sulfones from arylsulfonyl chlorides with Umemoto's reagent II

A practical and efficient method for the synthesis of aryl trifluoromethyl sulfones has been developed by a tandem reaction of arylsulfonyl chlorides with Umemoto's reagent II. The advantageous features of this method are simple operation, mild reaction conditions, wide scope of substrates, high yield of products, and easy scalability.

A method of manufacturing a benzene derivative (trifluoromethylsulfonyl)

PROBLEM TO BE SOLVED: To provide a method for producing a (trifluoromethylsulfonyl)benzene derivative which is useful as a medicine, an agricultural chemical, a functional material and a production intermediate thereof. SOLUTION: In this method, a (trifluoromethylsulfonyl)benzene derivative is produced by reacting diaryliodonium salt represented by general formula (1) with trifluoromethanesulfinic acid salt in the presence of a copper (I) salt. (In the formula, R1, R2, R3, R4, R5, R6, R7, R8, R9and R10each independently represents a hydrogen atom, a 1-6C alkyl group, a 1-6C haloalkyl group, a 1-6C alkoxy group, a 2-6C acyl group, (1-5C alkoxy)carbonyl group, a nitro group, a cyano group, a chlorine atom or a bromine atom). COPYRIGHT: (C)2013,JPOandINPIT