400-28-2 Usage
General Description
(E)-3-(Trifluoromethyl)crotonic acid is a compound with the chemical formula C5H5F3O2. It is a carboxylic acid with a trifluoromethyl group attached to a crotonic acid backbone. (E)-3-(Trifluoromethyl)crotonic acid is used in organic synthesis as a precursor to other fluorinated compounds. It is also employed as a building block in the production of pharmaceuticals and agrochemicals. Additionally, (E)-3-(Trifluoromethyl)crotonic acid has potential applications in the development of materials for electronic and optical devices due to its unique electronic and structural properties. Overall, this chemical exhibits versatility and potential for various industrial and research purposes.
Check Digit Verification of cas no
The CAS Registry Mumber 400-28-2 includes 6 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 3 digits, 4,0 and 0 respectively; the second part has 2 digits, 2 and 8 respectively.
Calculate Digit Verification of CAS Registry Number 400-28:
(5*4)+(4*0)+(3*0)+(2*2)+(1*8)=32
32 % 10 = 2
So 400-28-2 is a valid CAS Registry Number.
400-28-2Relevant articles and documents
Isothiourea-catalysed transfer hydrogenation of α,β-unsaturated para-nitrophenyl esters
Smith, Andrew D.,Wu, Jiufeng,Young, Claire M.
supporting information, (2020/12/21)
A protocol for the isothiourea-catalysed transfer hydrogenation of α,β-unsaturated para-nitrophenyl esters using Hantzsch ester has been developed. Good to excellent yields are observed using α,β-unsaturated aryl esters bearing electron-withdrawing β-subs
Catalytic asymmetric hydrogenation of α-CF3- or β-CF3-Substituted acrylic acids using Rhodium(I) complexes with a combination of chiral and achiral ligands
Dong, Kaiwu,Li, Yang,Wang, Zheng,Ding, Kuiling
supporting information, p. 14191 - 14195 (2014/01/06)
Only the mixture works! Acrylic acid derivatives with CF3 substituents in α or β position were efficiently hydrogenated in the presence of a RhI complex with a chiral secondary phosphine oxide (SPO; see scheme) and an achiral Ph3P as ligands. The corresponding propanoic acid derivatives were obtained with generally high conversion (>99 %) and high enantioselectivity (92->99 %). Copyright
